The High-Risk Benign Breast Lesion ProjectHigh-Risk Lesion Flow Chart

Many women undergoing breast cancer screening and diagnostic imaging are diagnosed with high-risk benign breast lesions. There is clinical uncertainty as to how aggressively to manage these cases with surgical excision, chemoprevention, and surveillance imaging. The VBCSS and their research partners at the Breast Cancer Surveillance Consortium (BCSC), are excited to develop and validate new statistical risk models for short and long-term breast cancer risk among women diagnosed with high-risk breast lesions.  This will inform clinical practice and national guidelines for identifying cases that require aggressive interventions while sparing others from unnecessary side effects. The VBCSS is using existing clinical data from our repository, as well as data collected by the five other sites across the U.S. that make up the Breast Cancer Surveillance Consortium (BCSC), to carry out this study.

The VBCSS is excited to be partnering with both our national colleagues, the Carolina Mammography Registry, the Kaiser Permanente Washington Breast Cancer Surveillance Registry, the San Francisco Mammography Registry, the Sacramento Area Breast Imaging Registry, and the New Hampshire Mammography Network, as well as UVM researchers Donald Weaver, MD, Thomas Ahern, PhDHannah Perry, MD, and Michelle Sowden, DO on this collaborative project! 

This project is funded by grant R01 CA282725 from the National Cancer Institute (NCI).