SELECTED PUBLICATIONS

(2016-2024)

2024

Cipolla M.J., Tremble S.M. (2024) Stroke in Pregnancy and Preeclampsia: Effect of Low-Dose Aspirin Treatment on Collateral Flow Velocity and Cerebral Blood Flow Autoregulation During Ischemia in Rats.  Journal of the American Heart Association. PMID: 38934871

O'Brien O.M., Tremble S.M., Kropf A., Cipolla M.J. (2024) Thrombin in Pregnancy and Preeclampsia: Expression, Localization, and Vasoactivity in Brain and Microvessels From Rats. Journal of Cardiovascular Pharmacology; 84(2):250-260. PMID: 38922586

Anderson J.L., McGreer J.A., Tremble S.M., Tainter-Gilbert A.V., Cipolla M.J. (2024) Differential Effects of LOX-1 Inhibition on Aortic Structure and Posterior Cerebral Artery Structure and Function in an Experimental Model of Preeclampsia.  Reproductive Sciences.; 84(2):250-260. PMID: 38858329

Hunt, R. D., & Cipolla, M. J. (2024) Chronic hypertension alters the relationship between collateral blood flow, cortical cerebral blood flow, and Brain Tissue Oxygenation.  Journal of Cerebral Blood Flow & Metabolism. PMID: 38806143

Mead, A. F., Wood, N. B., Nelson, S. R., Palmer, B. M., Yang, L., Previs, S. B., Ploysangngam, A., Kennedy, G. G., McAdow, J. F., Tremble, S. M., Cipolla, M. J., Ebert, A. M., Johnson, A. N., Gurnett, C. A., Previs, M. J., & Warshaw, D. M. (2024).  Functional role of myosin-binding protein H in thick filaments of developing vertebrate fast-twitch skeletal muscle. bioRxiv. PMID: 38798399

Esposito, M., Gatto, M., Cipolla, M. J., Bernstein, I. M., & Mandalà, M. (2024).  Dilation of pregnant rat uterine arteries with phenols from extra virgin olive oil is endothelium-dependent and involves calcium and potassium channels.  Cells, 13(7), 619. PMID: 38607058

Cipolla MJ, Hunt RD, Liebeskind DS, Tremble SM (2024). The impact of collateral therapeutics on stroke hemodynamics in normotensive and hypertensive rats: a step toward translation.  Frontiers in Neurology.  (Online Ahead of Print)

 

2023

Hunt RD, Sedighi O, Clark WM, Doiron AL, Cipolla MJ (2023). Differential effect of gold nanoparticles on cerebrovascular function and biomechanical properties. Physiological Reports. 11(16):e15789

Alkayed NJ, Cipolla MJ (2023).  The Ever-Evolving Concept of the Neurovascular UnitStroke. 54(8): 2178-2180. PMID:  37395105

Cipolla, MJ and Alkayed, NJ (2023). Vascular Biology of Dementia. Stroke. 54(3):646-647. PMID: 36848429

Cipolla, MJ (2023). Therapeutic Induction of Collateral FlowTransl Stroke Res. 14(1):53-65. PMID: 35416577

Khan SS, Brewer LC, Canobbio MM, Cipolla MJ, Grobman WA, Lewey J, Michos ED, Miller EC, Perak AM, Wei GS, Gooding H; American Heart Association Council on Epidemiology and Prevention; Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Hypertension; Council on Lifestyle and Cardiometabolic Health; Council on Peripheral Vascular Disease; and Stroke Council (2023). Optimizing Prepregnancy Cardiovascular Health to Improve Outcomes in Pregnant and Postpartum Individuals and Offspring: A Scientific Statement From the American Heart Association. Circulation. 147(7):e76-e91. PMID: 36780391

Cipolla MJ, Tremble SM, DeLance N, Johnson AC (2023). Worsened Stroke Outcome in a Model of Preeclampsia is Associated With Poor Collateral Flow and Oxidative StressStroke. 54(2):354-363. PMID: 36689585

 

2022

Wahlberg K, Mughal A, Li Z, Cipolla MJ, Cushman M, Flyer JN (2022). Retrospective study of medical student scholarship and career trajectory following a mentored preclinical cardiovascular summer research fellowship.  BMJ. 12(9):e059629. PMID: 36581970

Alkayed NJ, Cipolla MJ (2022). Role of Endothelial Cells and Platelets in COVID-Related Cerebrovascular Events. Stroke 53(7):2389-2392. PMID: 35674044

Whitaker EE, Johnson AC, Tremble SM, McGinn C, DeLance N, Cipolla MJ (2022): Cerebral Blood Flow Autoregulation in Offspring From Experimentally Preeclamptic Rats and the Effect of Age. Front. Physiol. (Online Ahead of Print)

Johnson AC, Tremble SM, Cipolla MJ (2022):  Experimental Preeclampsia Causes Long-Lasting Hippocampal Vascular Dysfunction and Memory Impairment.  Front. Physiol.  (Online Ahead of Print)

Cipolla MJ (2022):  Therapeutic Induction of Collateral Flow.  Transl Stroke Res. PMID:  35416577 (Online Ahead of Print)

Cipolla MJ, Tremble S, DeLance N, Allison D, Johnson AC (2022): Treatment with apocynin selectively restores hippocampal arteriole function and seizure-induced hyperemia in a model of preeclampsia. Journal of Cerebral Blood Flow & Metabolism. PMID: 35137612 (Online ahead of print).

 

2021

Mandala M, Cipolla MJ (2021): Aging-Related Structural and Functional Changes in Cerebral Arteries: Caloric Restriction (CR) Intervention. Journal of Vascular Medicine & Surgery, 9(Suppl 7), 1000002. PMID: 34981030.

Li Z and Cipolla MJ (2021): Mechanisms of Flow-Mediated Dilation of Pial Collaterals and the Effect of Hypertension. Hypertension, 79(2), 457-467. PMID: 34856815.

Cipolla MJ (2021):  Thomas Willis Lecture: Targeting Brain Arterioles for Acute Stroke Treatment.  Stroke, 52(7), 2465-2477.  PMID:  34102855.

Alkayed NJ and Cipolla MJ  (2021):  Vascular Biology.  Stroke, 52(7), 2440-2441. PMID: 34078110.

Whitaker EE, Johnson AC, Miller JE, Lindner DP, Cipolla MJ (2021):  Abnormal Development of Cerebral Arteries and Veins in Offspring of Experimentally Preeclamptic Rats:  Potential Role in Perinatal StrokeMech Ageing Dev, 196, 111491 . PMID: 33864898.

 

2020

Johnson AC, Li Z, Orfila JE, Herson PA, Cipolla MJ (2020): Hippocampal Network Dysfunction as a Mechanism of Early-Onset Dementia After Preeclampsia and Eclampsia. Progress in Neurobiology 2020; doi: 10.1016/j.pneurobio.2020.101938.

Li Z, Lindner D, Bishop N, and Cipolla MJ (2020): Angiotensin converting enzyme inhibition reverses vasoconstriction and impaired dilation of pial collaterals in chronic hypertensionHypertension 76(1):226-235. PMC7289681.

Cipolla MJ and Chan SL (2020). Impact of Acute and Chronic Hypertension on Changes in Pial Collateral Tone in vivo During Transient Ischemia. Hypertension Sep;76(3):1019-1026.

Beard D, Li Z, Schneider A, Couch Y, Cipolla MJ, and Buchan A (2020). Rapamycin Induces an eNOS Dependent Increase in Brain Collateral Perfusion in Wistar and Spontaneously Hypertensive Rats. Stroke Sep;51(9):2834-2843.

Johnson AC, Miller JE, and Cipolla MJ (2020): Memory Impairment in Spontaneously Hypertensive Rats is Associated with Hippocampal Hypoperfusion and Hippocampal Vascular Dysfunction. J Cerebr Blood Flow Metab Apr;40(4):845-859.

 

2019

Herisson F, Zhou IY, Mawet J, Du E, Hajizadeh B, Qin T, Cipolla MJ, Sun PZ, Ayata C, Rost N (2019): Posterior reversible encephalopathy syndrome in stroke-prone spontaneously hypertensive rats on high-salt dietJ Cerebr Blood Flow Metab Jul;39(7):1232-1246.

Chan SL, Nelson MT and Cipolla MJ (2019): TRPV4 channels are involved in diminished myogenic tone in brain parenchymal arterioles in response to chronic hypoperfusion in miceActa Physiologica Feb;225(2):e13181. NIHMSID: 1005007.

 

2018

Li Z, Tremble SM, Cipolla MJ. (2018) Implications for understanding ischemic stroke as a sexually dimorphic disease: the role of pial collateral circulations. American Journal of Physiology. Heart and Circulatory Physiology 315(6):H1703-H1712.

Li Z, Bishop N, Chan S, Cipolla MJ. (2018) Effect of TTC Treatment on Immunohistochemically Quantitation of Collagen IV in Rats Brains after Stroke. Springer. Translational Stroke Research 9(5):499-505.

Cipolla MJ, Liebeskind DS, Chan SL (2018).  The importance of comorbidities in ischemic stroke:  Impact of hypertension on the cerebral circulationJ Cereb Blood Flow Metab. 38(12):2129-2149.

Chan SL, Bishop N, Li Z, Cipolla MJ (2018).  Inhibition of PAI (Plasminogen Activator Inhibitor)-1 Improves Brain Collateral Perfusion and Injury After Acute Ischemic Stroke in Aged Hypertensive RatsStroke 49(8):1969-1976.

Johnson AC, Cipolla MJ. (2018)  Impaired function of cerebral parenchymal arterioles in experimental preeclampsiaMicrovasc Res. 119:64-72.

Merhi Z, Buyuk E, Cipolla MJ. (2018) Advanced glycation end products alter steroidogenic gene expression by granulosa cells: an effect partially reversible by vitamin DMol Hum Reprod.  24(6):318-326.

Brussé IA, van den Berg CB, Duvekot JJ, Cipolla MJ, Steegers EAP, Visser GH (2018). Visual evoked potentials in women with and without preeclampsia during pregnancy and postpartumJ Hypertens 36(2):319-325.

Johnson AC, Hammer ES, Sakkaki S, Tremble SM, Holmes GL, Cipolla MJ (2018).  Inhibition of blood-brain barrier efflux transporters promotes seizure in pregnant rats: Role of circulating factors Brain Behav Immun  67:13-23.

Cipolla, MJ, Linfante I, Abuchowski A, Jubin R, Can SL (2018).  Pharmacologically increasing collateral perfusion during acute stroke using a carboxyhemoglobin gas transfer agent (SanguinateTM) in spontaneously hypertensive ratsJ Cereb Blood Flow Metab 38(5):755-766.

 

2017

Bosetti F, Koenig JI, Ayata C, Back SA, Becker K, Broderick JP, Carmichael ST, Cho S, Cipolla MJ, Corbett D, Corriveau RA, Cramer SC, Ferguson AR, Finklestein SP, Ford BD, Furie KL, Hemmen TM, Iadecola C, Jakeman LB, Janis S, Jauch EC, Johnston KC, Kochanek PM, Kohn H, Lo EH, Lyden PD, Mallard C, McCullough LD, McGavern LM, Meschia JF, Moy CS, Perez-Pinzon MA, Ramadan I, Savitz SI, Schwamm LH, Steinberg GK, Stenzel-Poore MP, Tymianski M, Warach S, Wechsler LR, Zhang JH, Koroshetz W (2017).  Translational Stroke Research: Vision and OpportunitiesStroke 48(9):2632-2637.

Chan, SL, Cipolla, MJ (2017).  Treatment with low dose fasudil for acute ischemic stroke in chronic hypertensionJ Cereb Blood Flow Metab 37(9):3262-3270.

Cipolla MJ, Biller J. (2017).   Persistent brain injury after preeclampsiaNeurology.  88(13):1216-1217.

Cipolla MJ, Sweet JG, Chan SL (2017).  Effect of hypertension and peroxynitrite decomposition with FeTMPyP on CBF and stroke outcomeJ Cereb Blood Flow Metab.  37(4):1276-1285.

Johnson AC, Cipolla MJ (2017).  Altered hippocampal arteriole structure and function in a rat model of preeclampsia: Potential role in impaired seizure-induced hyperemia J Cereb Blood Flow Metab 37(8):2857-2869.

 

2016

Bosetti F, Galis ZS, Bynoe MS, Charette M, Cipolla MJ, Del Zoppo GJ, Gould D, Hatsukami TS, Jones TL, Koenig JI, Lutty GA, Maric-Bilkan C, Stevens T, Tolunay HE, Koroshetz W (2016).   Small Blood Vessels: Big Health Problems?": Scientific Recommendations of the National Institutes of Health WorkshopJ Am Heart Assoc 5(11). pii: e004389.

Linfante I, Cipolla MJ (2016).  Improving Reperfusion Therapies in the Era of Mechanical ThrombectomyTransl Stroke Res 7(4):294-302.

Ahnstedt H, Sweet J, Cruden P, Bishop N, Cipolla MJ (2016).  Effects of Early Post-Ischemic Reperfusion and tPA on Cerebrovascular Function and Nitrosative Stress in Female RatsTransl Stroke Res 7(3):228-38.

Chan SL, Sweet JG, Bishop N, Cipolla MJ (2016).  Pial Collateral Reactivity During Hypertension and Aging: Understanding the Function of Collaterals for Stroke TherapyStroke 47(6):1618-25.

Merhi Z, Thornton K, Bonney E, Cipolla MJ, Charron MJ, Buyuk E (2016). Ovarian kisspeptin expression is related to age and to monocyte chemoattractant protein-1. J Assist Reprod Genet 33(4):535-43.

Babi MA, Gorman MJ, Cipolla MJ, Allen G, Al Jerdi S2, Clouser R, Commichau C (2016):  Ondansetron-related hemorrhagic posterior reversible encephalopathy syndrome (PRES) following gastric bypass Springerplus 5:18. doi: 10.1186/s40064-015-1644-9. eCollection 2016. 

Canavero I, Sherburne HA, Tremble SM, Clark WM, Cipolla MJ (2016).  Effects of Acute Stroke Serum on Non-Ischemic Cerebral and Mesenteric Vascular FunctionTransl Stroke Res 7(2):156-65.

Ahnstedt H, McCullough LD, Cipolla MJ (2016).  The Importance of Considering Sex Differences in Translational Stroke ResearchTransl Stroke Res 7(4):261-73).