Totman Lecture Series

2023

Mohamed Trebak, Ph.D.      Mohamed Trebak, Ph.D., Professor

University of Pittsburgh

Vascular Medicine Institute

Pittsburgh, PA

 

 "Rewiring the cellular calcium signaling toolkit in disease"

2022

Chris B. Schaffer, Ph.D, and Nozomi Nishimura, Ph.D.   Chris B. Schaffer, Ph.D., Professor, and Nozomi Nishimura, Ph.D., Associate Professor

Cornell University

Meining School of Biomedical Engineering

Ithaca, NY

 

                                   "Cappillary-level blood flow disruptions contribute to reduced blood flow in neurodegenerative and

.                                   cardiovascular disease"

 

2019

Serge Charpak, M.D., Ph.D., Research Director at INSERM, Paris, France  Serge Charpak, M.D., Ph.D.

Research Director, INSERM, University of Paris, 7-Denis Diderot, Paris, France

 

"Brain activation:  Bridging the gap between cellular microscopic and vascular mesoscopic signals"

2018

Susan Amara, Ph.D.

Susan G. Amara, Ph.D.

Scientific Director, Intramural Research Program, National Institute of Mental Health, NIH, Bethesda, MD

 

"Dynamic regulation of intracellular signaling pathways by amphetamines" 

 

 

 

2017

Jaime Grutzendler, M.D.

Professor of Neurology and Neuroscience, Vice-Chair for Research (Basic), Director of the Center for Experimental Neuroimaging, Director, Clinician Neuroscientist Training Program (CNSTP)

 

"In vivo optical interrogation of neurovascular function and pathology" 

 

2015

dkleinfeld_001David Kleinfeld, Ph.D.

 

Distinguished Professor, Experimental Biophysics Endowed Chair 2014-2019, Physiology, University of California at San Diego

"Cortical Blood Flow: From Vascular Topology to Vasomotor Dynamics"

2014

2014JKFoskett7938_000J. Kevin Foskett, Ph.D.

 

Professor and Chair - Physiology, University of Pennsylvania, Philadelphia, PA

"CALHM ion channels: How taste cells lacking synapses mediate neurotransmission"

2013

santana-biophoto-UCDavisLuis Fernando Santana, Ph.D.

Professor - University of Washington, Seattle WA

“Mechanisms of High Fidelity EC coupling in Heart”

 

 

 

 

Dr.KurtBeamreduced_000Kurt B. Beam, Ph.D.

Professor - University of Colorado, Denver, Anschutz Medical Campus, Aurora, CO


“Excitation-contraction coupling in skeletal muscle: investigating a 4 megadalton ion channel complex”

2012

edithhamelresized_000Edith Hamel, Ph.D.


Professor - Montreal Neurological Institute


“Neuronal networks in functional hyperemia: Selectivity through afferent input”
 

 

constantinoiadecola_000Costantino Iadecola, M.D.

 

G.C. Cotzias Distinguished Professor, Weill Cornell Medical College


“Neurovascular Coupling in Health and Disease: Mechanisms and Implications for Brain Function”

2011

annejoutelAnne Joutel, M.D., Ph.D.



Research Director - INSERM, University Paris

“Cadasil, as a paradigm to study small vessel disease of the brain”

 

 

 

dalepelligrinoDale A. Pelligrino, Ph.D.


Professor & Director, Neuroanesthesia Research Laboratory, Department of Anesthesiology, University of Illinois at Chicago


“Purinergic mechanisms in gliovascular coupling”

2010

PhilHaydonPhilip G. Haydon, Ph.D.


Annetta and Gustav Grisard Professor & Chair, Department of Neurosciences, Tufts University School of Medicine


“Glia & Sleep”
 

andymarksAndrew Marks, M.D.


Wu Professor & Chair, Department of Physiology and Cellular Biophysics, Columbia University College of Physicians and Surgeons, Founding Director, Helen and Clyde Wu Center for Molecular Cardiology


“Intercellular calcium leak role in disorders of heart, muscle and brain”

 

Soren-PeterOlesenSoren-Peter Olesen, M.D., Ph.D.


Professor, Department of Biomedical Sciences, University of Copenhagen


“Pharmacological regulation of SK and BK channels in the heart”

2009

johngarthwaiteJohn Garthwaite, Ph.D.


Professor of Experimental Neuroscience, The Wolfson Institute for Biomedical Research, University College London


“Neural nitric oxide-mediated transmission: how does it work?”

 

 

avrilsomyloAvril V. Somlyo, Ph.D.


Professor, Department of Molecular Physiology & Biological Physics, University of Virginia School of Medicine


"Molecular Physiology of calcium Activated Potassium Channels"

2008

richardaldrichRichard W. Aldrich, Ph.D.


Professor & Chair of Neurobiology, University of Texas at Austin


"Molecular Physiology of calcium Activated Potassium Channels"

 

 

richardlewisRichard S. Lewis, Ph.D.


Professor & Chair of Neurobiology, Stanford University


"Sensor seeks channel for intimate interactions: a molecular mechanism for store-operated calcium entry"

2007

rockykassRobert S. Kass, Ph.D.


Chairman and Alumni and David Hosak Professor, Pharmacology, Columbia University

"General Lessons from Rare Congenital Arrhythmias: Implications for Personal Medicine and Mechanistic Basis of Disease"

 

 

 

nickstandenNicholas B. Standen, Ph.D.


Professor of Cell Physiology & Pharmacology, University of Leicester


"Effects of downregulating cardiac KATP channels on the response of cardiac muscle to stress"

2006

mikemendelsohnMichael E. Mendelsohn, M.D.


Professor of Medicine, Physiology & Biochemistry, Tufts University


"Regulation of Vascular Function and Blood Pressure by Cyclic BMP - dependent Protein Kinases"

2005

davidclaphamDavid Clapham, M.D., Ph.D.


Aldo R. Castaneda Professor of Cardiovascular Research, Howard Hughes Medical Institute, Children's Hospital, Boston, Professor of Neurobiology, Harvard Medical School


"TRP Ion Channels"

2004

mikekotllikoffMichael I. Kotlikoff, V.M.D., Ph.D.


Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University


"Reporter Mice and In Vivo Physiology"

2003

johnledererW. Jonathan Lederer, M.D., Ph.D.


Physiology and Medical Biotech Center University of Maryland


"Occluded Elements in Local Calcium Signaling"

2002

kentsandersKenton M. Sanders, Ph.D.

Professor & Chairman, Department of Physiology & Cell Biology, University of Nevada School of Medicine

"Electrical Rhythmicity Mechanisms in Gastrointestinal Smooth Muscles"

2001

davidclaphamDavid Clapham, M.D., Ph.D.


Aldo R. Castaneda Professor of Cardiovascular Research, Howard Hughes Medical Institute, Children's Hospital, Boston


"Calcium Entry Ion Channels – from Life to Death"

2000

suepiperducklesSue Piper Duckles, Ph.D.


Professor, Department of Pharmacology, University of California, Irvine


"Effects of Estrogen on Cerebral Blood Vessels"

Serge Charpak, M.D., Ph.D. Research Dir. INSERM, Paris, FR