Publications Archives

View papers published from the MIC, sorted by instrument.

Transmission Electron Microscope

 

  • Munson, P. B., et al. (2019). "Exosomal miR-16-5p as a target for malignant mesothelioma." Sci Rep 9(1): 11688.
  • Guigni, B. A., et al. (2018). "Skeletal muscle atrophy and dysfunction in breast cancer patients: role for chemotherapy-derived oxidant stress." Am J Physiol Cell Physiol 315(5): C744-C756
  • Munson, P., et al. (2018). "Exosomes from asbestos-exposed cells modulate gene expression in mesothelial cells." FASEB J 32(8): 4328-4342.
  • Munson, P., et al. (2018). "Mouse serum exosomal proteomic signature in response to asbestos exposure." J Cell Biochem 119(7): 6266-6273.
  • Ribis, J. W., et al. (2018). "Differential requirements for conserved peptidoglycan remodeling enzymes during Clostridioides difficile spore formation." Mol Microbiol 110(3): 370-389.
  • Pearson, L., et al. (2018). "A Composite Renal Tumor with Dual Differentiation, Chromophobe and Collecting Duct Carcinoma." Case Rep Pathol 2018: 2410920.
  • Wrenn, S. M., et al. (2018). "Avian lungs: A novel scaffold for lung bioengineering." PLoS One 13(6): e0198956.
  • MacPherson, M., et al. (2017). "Actin polymerization plays a significant role in asbestos-induced inflammasome activation in mesothelial cells in vitro." Histochem Cell Biol 147(5): 595-604.
  • Miller, M. S., et al. (2017). "Moderate-intensity resistance exercise alters skeletal muscle molecular and cellular structure and function in inactive older adults with knee osteoarthritis." J Appl Physiol (1985) 122(4): 775-787.
  • Ribis, J. W., et al. (2017). "The Conserved Spore Coat Protein SpoVM Is Largely Dispensable in Clostridium difficile Spore Formation." mSphere 2(5).
  • Thwe, P. M., et al. (2017). "Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses." Cell Metab 26(3): 558-567 e555.
  • Uhl, F. E., et al. (2017). "Preparation of Decellularized Lung Matrices for Cell Culture and Protein Analysis." Methods Mol Biol 1627: 253-283.
  • Buskiewicz, I. A., et al. (2016). "Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus." Sci Signal 9(456): ra115.
  • Ondzighi-Assoume, C. A., et al. (2016). "Environmental Nitrate Stimulates Abscisic Acid Accumulation in Arabidopsis Root Tips by Releasing It from Inactive Stores." Plant Cell 28(3): 729-745.
  • Platz, J., et al. (2016). "Comparative Decellularization and Recellularization of Wild-Type and Alpha 1,3 Galactosyltransferase Knockout Pig Lungs: A Model for Ex Vivo Xenogeneic Lung Bioengineering and Transplantation." Tissue Eng Part C Methods 22(8): 725-739.
  • Naik, A. R., Kulkarni, S. P., Lewis, K. T., Taatjes, D. J., and Jena, B. P. (2016) Functional reconstitution of the insulin-secreting porosome complex in live cells. Endocrinology 157, 54-60.
  • Clemments, A. M., et al. (2015). "Protein Adsorption From Biofluids on Silica Nanoparticles: Corona Analysis as a Function of Particle Diameter and Porosity." ACS Appl Mater Interfaces 7(39): 21682-21689.
  • Cruz, F. F., et al. (2015). "Systemic Administration of Human Bone Marrow-Derived Mesenchymal Stromal Cell Extracellular Vesicles Ameliorates Aspergillus Hyphal Extract-Induced Allergic Airway Inflammation in Immunocompetent Mice." Stem Cells Transl Med 4(11): 1302-1316.
  • Pappas, A. C., et al. (2015). "Astrocyte Ca2+ Signaling Drives Inversion of Neurovascular Coupling after Subarachnoid Hemorrhage." J Neurosci 35(39): 13375-13384.
  • Yang, R., Lirussi, D., Thornton, T.M., Jelley-Gibbs, D.M., Gummadidala, P., Diehl, S.A., Case, L.K., Silverstrim, B., Madesh, M., Taatjes, D.J., O’Shea, J.J., Teuscher, C., Haynes, L., and Rincon, M. (2015) Mitochondrial Ca2+ and membrane potential, an alternative pathway for Interleukin 6 to regulate CD4 cell effector function. eLife 2015;4;e06376.
  • Fang, J., Liu, M., Zhang, X., Sakamoto, T., Taatjes, D.J., Jena, B.P., Sun, F., Woods, J., Bryson, T., Kowluru, A., Zhang, K., and Chen, X. (2015) COPII dependent ER export: a critical component of insulin biogenesis and beta cell ER homeostasis. Mol. Endocrinol. 29, 1156-1169.
  • Pishdadian K, Fimlaid KF, Shen A. (2015) SpoIIID-mediated regulation of sK function during Clostridium diffiile sporulation. Mol Microbiol. Jan;95(2):189-208.
  • Fimlaid KA, Jensen O, Francis MB, Sorg JA, Shen A. (2015) Identification of a novel lipoprotein regulator of Clostridium difficile spore germination. PLoS Pathogens. Oct 23;11(10):e1005239.
  • Fimlaid KA, Jensen O, Donnelly ML, Siegrist MS, Shen A. (2015) Regulation of Clostridium difficile spore formation by the SpoIIQ and SpoIIIA proteins. PLoS Genetics. Oct 14;11(10):e1005562.
  • Wang, Y., Bishop, N.M., Taatjes, D.J., Narisawa, S., Millan, J.L., and Palmer, B.M. (2014) Sex-dependent, zinc-induced de-phosphorylation of phospholamban by tissue non-specific alkaline phosphatase in the cardiac sarcomere. Am. J. Physiol. Heart Circ. Physiol. 307, H933-H938.
  • Rajagopal, A., Kulkarni, S., Lewis, K.T., Maarouf, A., Kelly, C.V., Taatjes, D.J., and Jena, B.P. (2014) Proteome of the insulin-secreting Min6 porosome complex: Involvement of Hsp90 in its assembly and function. J. Proteom. 114, 83-92.
  • Hou X, Lewis KT, Wu Q, Wang S, Chen X, Flack A, Mao G, Taatjes DJ, Sun F, Jena BP. (2014) Proteome of the porosome complex in human airway epithelia: interaction with the cystic fibrosis transmembrane conductance regulator (CFTR). J Proteomics. Jan 16;96:82-91.
  • Kovari LC, Brunzelle JS, Lewis KT, Cho WJ, Lee JS, Taatjes DJ, Jena BP. (2014) X-ray solution structure of the native neuronal porosome-synaptic vesicle complex: Implication in neurotransmitter release. Micron. Jan;56:37-43.
  • Wang, S., Lee, J-S., Bishop, N., Jeremic, A., Cho, W.J., Chen, X., Mao, G., Taatjes, D.J., and Jena, B.P. (2012) 3D organization and function of the cell: Golgi budding and vesicle biogenesis to docking at the porosome complex. Histochem. Cell Biol. 137, 703-718.
  • Donaldson C, Taatjes DJ, Zile M, Palmer B, VanBuren P, Spinale F, Maughan D, von Turkovich M, Bishop N, LeWinter MM. (2010) Combined immunoelectron microscopic and computer-assisted image analyses to detect advanced glycation end-products in human myocardium. Histochem. Cell Biol. 134, 23-30.
  • French CJ, Taatjes DJ, Sobel BE. (2010) The extent of autophagy in myocardium of murine hearts subjected to ischemia followed by reperfusion. Histochem. Cell Biol. 134, 519-526.
  • Hillegass JM, Blumen SR, Cheng K, MacPherson MB, Alexeeva V, Lathrop SA, Beuschel SL, Steinbacher JL, Butnor KJ, Ramos-Nino ME, Shukla A, James TA, Weiss DJ, Taatjes DJ, Pass HI, Carbone M, Landry CC, Mossman BT. (2010) Increase efficacy of doxorubicin delivered in multifunctional microparticles for mesothlioma therapy. Int. J. Cancer. In press.
  • French CJ, Spees JL, Zaman AKMT, Taatjes DJ, Sobel BE. (2009) The magnitude and temporal dependence of apoptosis early after myocardial ischemia with or without reperfusion. FASEB. 23, 1177-1185.
  • Hatle KM, Neveu W, Dienz O, Rymarchyk S, Barrantes R, Hale S, Farley N, Lounsbury KM, Bond JP, Taatjes DJ, Rincon M. (2007) MCJ promotes c-Jun degradation to prevent ABCB1 transporter expression. Mol. Cell Biol. 27, 2952-2966.
  • Storch KN, Taatjes DJ, Bouffard NA, Locknar S, Bishop NM, Langevin HM. (2007) Alpha-Smooth muscle actin distribution in cytoplasm and nuclear invaginations of connective tissue fibroblasts. Histochem. Cell Biol. 127, 523-530.

Scanning Electron Microscope

 

  • Liu, Z. W., R.; Du, F.; Giles, C.; Dewoolkar M.; Huston, D.; Tan, T. (2021). "A study on avalanches of early age basalt fiber reinforced concrete beams during flexure." Journal of Cleaner Production 279.              
  • Liu, Z. W., R.; Du, F.; Giles, C.; Dewoolkar M.; Huston, D.; Tan, T. (2020). "Avalanches during flexure of early-age steel fiber reinforced concrete beams." Materials and Structures 53(76): 1-20.              
  • Liu, Z. W., R.; Du, F.; Giles, C.; Dewoolkar M.; Huston, D.; Tan, T. (2020). "Measurement of stress-time avalanches inside polypropylene fiber reinforced concrete beams during flexure." Construction and Building Materials.
  • Kostyun, J. L., et al. (2019). "Evidence of a largely staminal origin for the Jaltomata calliantha (Solanaceae) floral corona." Evodevo 10: 9.
  • Li, Y., et al. (2019). "An experimental study on adhesion between steel and cement pastes using particle probe scanning force microscopy." Journal of the American Ceramic Society 102(3): 1347-1361.
  • Preston, J. C., et al. (2019). "Implications of region-specific gene expression for development of the partially fused petunia corolla." Plant J.
  • Alghamdi, S., et al. (2018). "The role of water in the initial sliding of nacreous tablets: Findings from the torsional fracture of dry and hydrated nacre." J Mech Behav Biomed Mater 88: 322-329.
  • Bouchard, B. A., et al. (2018). "Microparticles formed during storage of red blood cell units support thrombin generation." J Trauma Acute Care Surg 84(4): 598-605.
  • Hamlington, K. L., et al. (2018). "Linking lung function to structural damage of alveolar epithelium in ventilator-induced lung injury." Respir Physiol Neurobiol 255: 22-29.
  • Munson, P., et al. (2018). "Exosomes from asbestos-exposed cells modulate gene expression in mesothelial cells." FASEB J 32(8): 4328-4342.
  • Rand, J. H. and D. J. Taatjes (2018). "Reimagining the antiphospholipid syndrome, an enigmatic thrombophilic disorder, through the looking glass of microscopic imaging." Histochem Cell Biol 150(5): 529-543.
  • Alghamdi, S., et al. (2017). "Catastrophic failure of nacre under pure shear stresses of torsion." Sci Rep 7(1): 13123.
  • Gupta, D., et al. (2017). "Temporal characterization of beta cell-adaptive and -maladaptive mechanisms during chronic high-fat feeding in C57BL/6NTac mice." J Biol Chem 292(30): 12449-12459.
  • Fenn, S. L., et al. (2016). "Dual-Cross-Linked Methacrylated Alginate Sub-Microspheres for Intracellular Chemotherapeutic Delivery." ACS Appl Mater Interfaces 8(28): 17775-17783.
  • Kaiser, S., et al. (2015). "Exploratory use of docetaxel loaded acid-prepared mesoporous spheres for the treatment of malignant melanoma." Cancer Nanotechnol 6: 1.
  • Lee, J-S., Agrawal, S., von Turkovich, M., Taatjes, D.J., Walz, D.A., and Jena, B.P. (2012) Water channels in platelet volume regulation. J. Cell. Molec. Med. 16, 945-949.

Confocal Laser Microscopy

 

  • Kumar, A., et al. (2022). "Inhibition of PDIA3 in club cells attenuates osteopontin production and lung fibrosis." Thorax 77(7): 669-678.
  • Palmer, B. M. and S. P. Bell (2022). "Preparing Excitable Cardiac Papillary Muscle and Cardiac Slices for Functional Analyses." Front Physiol 13: 817205.
  • Taatjes D.J.; Ghule P.N., B. N. A., Lee K., DeLance N.M., Evans M.F., Weaver D.L., Deakin N., Carr F.E., Sprague B.L., Stein G.S., Stein J.L. (2022). "The Shared Core Resource as a Partner in Innovative Scientific Research: Illustration from an Academic Microscopy Imaging Center." Journal of Biomedical Techniques 33(1).
  • Bruno, S. R., et al. (2021). "DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen." Int J Mol Sci 22(20).
  • Gasek, N., et al. (2021). "Comparative immunogenicity of decellularized wild type and alpha 1,3 galactosyltransferase knockout pig lungs." Biomaterials 276: 121029.
  • Gokina, N. I., et al. (2021). "Deficiency in CD4 T Cells Leads to Enhanced Postpartum Internal Carotid Artery Vasoconstriction in Mice: The Role of Nitric Oxide." Front Physiol 12: 686429.
  • Ikeh, K. E., et al. (2021). "REV1 Inhibition Enhances Radioresistance and Autophagy." Cancers (Basel) 13(21).
  • Johnson, A. C., et al. (2021). "Hippocampal network dysfunction as a mechanism of early-onset dementia after preeclampsia and eclampsia." Prog Neurobiol 199: 101938.
  • Sepaniac, L. A., et al. (2021). "Micronuclei in Kif18a mutant mice form stable micronuclear envelopes and do not promote tumorigenesis." J Cell Biol 220(11).
  • Chia, S. B., et al. (2020). "Glutaredoxin deficiency promotes activation of the transforming growth factor beta pathway in airway epithelial cells, in association with fibrotic airway remodeling." Redox Biol 37: 101720.
  • Li, Z., et al. (2020). "ACE (Angiotensin-Converting Enzyme) Inhibition Reverses Vasoconstriction and Impaired Dilation of Pial Collaterals in Chronic Hypertension." Hypertension 76(1): 226-235.
  • Rose, J. T., et al. (2020). "Inhibition of the RUNX1-CBFbeta transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking." Oncotarget 11(26): 2512-2530.
  • Chamberlain, N., et al. (2019). "Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics." Redox Biol 22: 101129.
  • Danforth, D. R., et al. (2019). "A Nonfimbrial Adhesin of Aggregatibacter actinomycetemcomitans Mediates Biofilm Biogenesis." Infect Immun 87(1).
  • Li, A., et al. (2019). "Skeletal MyBP-C isoforms tune the molecular contractility of divergent skeletal muscle systems." Proc Natl Acad Sci U S A 116(43): 21882-21892.
  • Little, A. C., et al. (2019). "Dysregulated Redox Regulation Contributes to Nuclear EGFR Localization and Pathogenicity in Lung Cancer." Sci Rep 9(1): 4844.
  • Munson, P. B., et al. (2019). "Exosomal miR-16-5p as a target for malignant mesothelioma." Sci Rep 9(1): 11688.
  • Tarr, E. A., et al. (2019). "Distribution of FMRFamide-related peptides and co-localization with glutamate in Cupiennius salei, an invertebrate model system." Cell Tissue Res 376(1): 83-96.
  • Yacawych, W. T., et al. (2019). "Insulin receptor localization in the embryonic avian hypothalamus." Neurosci Lett 698: 126-132.
  • Anathy, V., et al. (2018). "Reducing protein oxidation reverses lung fibrosis." Nat Med 24(8): 1128-1135.
  • Campen, K. A., et al. (2018). "Spindle abnormalities and chromosome misalignment in bovine oocytes after exposure to low doses of bisphenol A or bisphenol S." Hum Reprod 33(5): 895-904
  • Chan, S. L., et al. (2018). "Inhibition of PAI (Plasminogen Activator Inhibitor)-1 Improves Brain Collateral Perfusion and Injury After Acute Ischemic Stroke in Aged Hypertensive Rats." Stroke 49(8): 1969-1976.
  • Fritz, A. J., et al. (2018). "Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer." J Cell Physiol 233(2): 1278-1290.             
  • Gertz, J. M., et al. (2018). "Endocytosed factor V is trafficked to CD42b(+) proplatelet extensions during differentiation of human umbilical cord blood-derived megakaryocytes." J Cell Physiol 233(11): 8691-8700.
  • Gillis, N. E., et al. (2018). "Thyroid Hormone Receptor beta Suppression of RUNX2 Is Mediated by Brahma-Related Gene 1-Dependent Chromatin Remodeling." Endocrinology 159(6): 2484-2494.
  • Jha, S. G., et al. (2018). "Vacuolar Protein Sorting 26C encodes an evolutionarily conserved large retromer subunit in eukaryotes that is important for root hair growth in Arabidopsis thaliana." Plant J 94(4): 595-611.
  • John, L., et al. (2018). "The Piezo1 cation channel mediates uterine artery shear stress mechanotransduction and vasodilation during rat pregnancy." Am J Physiol Heart Circ Physiol 315(4): H1019-H1026.
  • Johnson, A. C., et al. (2018). "Inhibition of blood-brain barrier efflux transporters promotes seizure in pregnant rats: Role of circulating factors." Brain Behav Immun 67: 13-23.
  • Ma, D., et al. (2018). "Measurement of ultrasound-enhanced diffusion coefficient of nanoparticles in an agarose hydrogel." J Acoust Soc Am 144(6): 3496.
  • McDaniel, J. R., et al. (2018). "Identification of tumor-reactive B cells and systemic IgG in breast cancer based on clonal frequency in the sentinel lymph node." Cancer Immunol Immunother 67(5): 729-738.
  • Qian, X., et al. (2018). "IL-1/inhibitory kappaB kinase epsilon-induced glycolysis augment epithelial effector function and promote allergic airways disease." J Allergy Clin Immunol 142(2): 435-450 e410.
  • Rand, J. H. and D. J. Taatjes (2018). "Reimagining the antiphospholipid syndrome, an enigmatic thrombophilic disorder, through the looking glass of microscopic imaging." Histochem Cell Biol 150(5): 529-543.
  • Thompson, J. K., et al. (2018). "Extracellular signal regulated kinase 5 and inflammasome in progression of mesothelioma." Oncotarget 9(1): 293-305.
  • Thornton, T. M., et al. (2018). "Failure to Inactivate Nuclear GSK3beta by Ser(389)-Phosphorylation Leads to Focal Neuronal Death and Prolonged Fear Response." Neuropsychopharmacology 43(2): 393-405.
  • Tracy, K. M., et al. (2018). "Mitotically-Associated lncRNA (MANCR) Affects Genomic Stability and Cell Division in Aggressive Breast Cancer." Mol Cancer Res 16(4): 587-598.
  • van der Velden, J. L., et al. (2018). "TGF-beta1-induced deposition of provisional extracellular matrix by tracheal basal cells promotes epithelial-to-mesenchymal transition in a c-Jun NH2-terminal kinase-1-dependent manner." Am J Physiol Lung Cell Mol Physiol 314(6): L984-L997.
  • Wrenn, S. M., et al. (2018). "Avian lungs: A novel scaffold for lung bioengineering." PLoS One 13(6): e0198956.
  • Zhao, F. Q., et al. (2018). "Differential expression of Oct3/4 in human breast cancer and normal tissues." Int J Oncol 52(6): 2069-2078.
  • Ziegler, C. M., et al. (2018). "The use of novel epitope-tagged arenaviruses reveals that Rab5c-positive endosomal membranes are targeted by the LCMV matrix protein." J Gen Virol 99(2): 187-193/
  • Fabian-Fine, R., et al. (2017). "The distribution of cholinergic neurons and their co-localization with FMRFamide, in central and peripheral neurons of the spider Cupiennius salei." Cell Tissue Res 370(1): 71-88.
  • Galick, H. A., et al. (2017). "The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation." Oncotarget 8(49): 85883-85895.
  • Gupta, D., et al. (2017). "Temporal characterization of beta cell-adaptive and -maladaptive mechanisms during chronic high-fat feeding in C57BL/6NTac mice." J Biol Chem 292(30): 12449-12459.
  • Johnson, A. C. and M. J. Cipolla (2017). "Altered hippocampal arteriole structure and function in a rat model of preeclampsia: Potential role in impaired seizure-induced hyperemia." J Cereb Blood Flow Metab 37(8): 2857-2869.
  • King, B. R., et al. (2017). "A Map of the Arenavirus Nucleoprotein-Host Protein Interactome Reveals that Junin Virus Selectively Impairs the Antiviral Activity of Double-Stranded RNA-Activated Protein Kinase (PKR)." J Virol 91(15).
  • Liu, Z., et al. (2017). "Vascular disease-causing mutation, smooth muscle alpha-actin R258C, dominantly suppresses functions of alpha-actin in human patient fibroblasts." Proc Natl Acad Sci U S A 114(28): E5569-E5578.
  • MacPherson, M., et al. (2017). "Actin polymerization plays a significant role in asbestos-induced inflammasome activation in mesothelial cells in vitro." Histochem Cell Biol 147(5): 595-604.
  • Pociask, D. A., et al. (2017). "Epigenetic and Transcriptomic Regulation of Lung Repair during Recovery from Influenza Infection." Am J Pathol 187(4): 851-863.
  • Uhl, F. E., et al. (2017). "Preparation of Decellularized Lung Matrices for Cell Culture and Protein Analysis." Methods Mol Biol 1627: 253-283.
  • Villalba, N., et al. (2017). "Traumatic Brain Injury Causes Endothelial Dysfunction in the Systemic Microcirculation through Arginase-1-Dependent Uncoupling of Endothelial Nitric Oxide Synthase." J Neurotrauma 34(1): 192-203.
  • Ahnstedt, H., et al. (2016). "Effects of Early Post-Ischemic Reperfusion and tPA on Cerebrovascular Function and Nitrosative Stress in Female Rats." Transl Stroke Res 7(3): 228-238.
  • Buskiewicz, I. A., et al. (2016). "Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus." Sci Signal 9(456): ra115.
  • Carr, F. E., et al. (2016). "Thyroid Hormone Receptor-beta (TRbeta) Mediates Runt-Related Transcription Factor 2 (Runx2) Expression in Thyroid Cancer Cells: A Novel Signaling Pathway in Thyroid Cancer." Endocrinology 157(8): 3278-3292.
  • Champagne, D. P., et al. (2016). "Fine-Tuning of CD8(+) T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus." Immunity 44(6): 1299-1311.
  • Chihabi, K., et al. (2016). "Intracerebellar infusion of the protein kinase M zeta (PKMzeta) inhibitor zeta-inhibitory peptide (ZIP) disrupts eyeblink classical conditioning." Behav Neurosci 130(6): 563-571.
  • Ghule, P. N., et al. (2016). "Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos." Dev Biol 419(2): 311-320.
  • Hristova, M., et al. (2016). "Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses." J Allergy Clin Immunol 137(5): 1545-1556 e1511.
  • Marsden, C. G., et al. (2016). "The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype." PLoS Genet 12(8): e1006208.
  • Ondzighi-Assoume, C. A., et al. (2016). "Environmental Nitrate Stimulates Abscisic Acid Accumulation in Arabidopsis Root Tips by Releasing It from Inactive Stores." Plant Cell 28(3): 729-745.
  • Platz, J., et al. (2016). "Comparative Decellularization and Recellularization of Wild-Type and Alpha 1,3 Galactosyltransferase Knockout Pig Lungs: A Model for Ex Vivo Xenogeneic Lung Bioengineering and Transplantation." Tissue Eng Part C Methods 22(8): 725-739.
  • Sckolnick, M., et al. (2016). "Tropomyosin isoforms bias actin track selection by vertebrate myosin Va." Mol Biol Cell 27(19): 2889-2897.             
  • Smith, K. P., et al. (2016). "Inner-membrane protein MorC is involved in fimbriae production and biofilm formation in Aggregatibacter actinomycetemcomitans." Microbiology 162(3): 513-525.
  • Thornton, T. M., et al. (2016). "Inactivation of nuclear GSK3beta by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response." Nat Commun 7: 10553.
  • van der Velden, J. L., et al. (2016). "JNK inhibition reduces lung remodeling and pulmonary fibrotic systemic markers." Clin Transl Med 5(1): 36.
  • Yang, R., et al. (2016). "IL-6 promotes the differentiation of a subset of naive CD8+ T cells into IL-21-producing B helper CD8+ T cells." J Exp Med 213(11): 2281-2291.
  • Mingin, G. C., et al. (2015). "Social stress in mice induces urinary bladder overactivity and increases TRPV1 channel-dependent afferent nerve activity." Am J Physiol Regul Integr Comp Physiol 309(6): R629-638.
  • Moon, T. M., et al. (2015). "Synthetic Peptides as cGMP-Independent Activators of cGMP-Dependent Protein Kinase Ialpha." Chem Biol 22(12): 1653-1661.

 

  • McMillan, D.H., van der Velden, J.L.J., Lahue, K.G., Qian, X., Schneider, R.W., Iberg, M.S., Nolin, J.D., Abdalla, S., Casey, D.T., Tew, K.D., Townsend, D.M., Henderson, C.J., Wolf, C.R., Butnor, K.J., Taatjes, D.J., Budd, R.C., Irvin, C.G., van der Vliet, A., Flemer, S., Anathy, V., and Janssen-Heininger, Y.M.W. (2016) Attenuation of lung fibrosis in mice with clinically-relevant inhibitor of glutathione S-transferase pi. J. Clin. Invest. Insight, In press.
  • Hoffman, S.M., Qian, X., Nolin, J.D., Chapman, D.G., Chia, S.B., Lahue, K.G., Schneider, R., Ather, J.L., Randall, M.J., McMillan, D.H., Jones, J.T., Taatjes, D.J., Aliyeva, M., Daphtary, N., Abdalla, S., Lundblad, L.K.A., Ho, Y-S., Anathy, V., Irvin, C.G.,, Wouters, E.F.M., Reynaert, N.L., Dixon, A.E., van der Vliet, A., Poynter, M.E., and Janssen-Heiniger, Y.M.W. (2016) Ablation of glutaredoxin-1 modulates house dust mite-induced allergic airways disease in mice. Am. J. Respir. Cell Mol. Biol., In press.
  • Yang, R., Lirussi, D., Thornton, T.M., Jelley-Gibbs, D.M., Gummadidala, P., Diehl, S.A., Case, L.K., Silverstrim, B., Madesh, M., Taatjes, D.J., O’Shea, J.J., Teuscher, C., Haynes, L., and Rincon, M. (2015) Mitochondrial Ca2+ and membrane potential, an alternative pathway for Interleukin 6 to regulate CD4 cell effector function. eLife 2015;4;e06376.
  • Klaus J, Eisenhauer P, Russo J, Mason A, Do D, King B, Taatjes D, Cornillez-Ty C, Boyson JE, Zheng C, Liao L, Yates JR III, Zhang B, Ballif BA, Botten J. (2013) The intracellular cargo receptor ERGIC-53 is required for the production of infectious arenavirus, coronavirus, and filovirus particles. Cell Host & Microbe. Nov;14: 522-534.
  • Macura, S.L., Hillegass, J.M., Steinbacher, J.L., MacPherson, M.B., Shukla, A., Beuschel, S.L., Perkins, T.N., Butnor, K.J., Lathrop, M.J., Hekmatyar, K., Taatjes, D.J., Kauppinen, R.A., Landry, C.C., and, Mossman, B.T. (2012) A multifunctional mesothelin antibody-tagged microparticle targets human mesotheliomas. J. Histochem. Cytochem., In press.
  • Trotman, W.E., Taatjes, D.J., Callas, P.W., and Bovill, E.G. (2011) The endothelial microenvironment in the venous valvular sinus: Thromboresistance trends and inter-individual variation. Histochem. Cell Biol. 135, 141-152.
  • Langevin HM, Storch KN, Snapp RR, Bouffard NA, Badger GJ, Howe AK, Taatjes DJ. (2010) Tissue stretch induces nuclear remodeling in connective tissue fibroblasts. Histochem. Cell Biol. 134, 23-30.
  • Aesif SW, Havermans M, Anathy V, Guala AS, Ckless K, Taatjes DJ, Janssen-Heininger YMW. (2009) In situ analysis of protein S-glutathionylation in lung tissue using glutaredoxin-1 catalyzed cysteine derivatization. Am. J. Pathol. 175, 36-45.
  • Brooks EG, Trotman W, Wadsworth MP, Taatjes DJ, Evans MF, Ittleman FP, Callas PW, Esmon CT, Bovill EG. (2009) Valves of the seep venous system: An overlooked risk factor. Blood. 114, 1276-1279.
  • Manning CB, Sabo-Attwood T, Robledo RF, MacPherson MB, Rincon M, Vacek P, Hemenway D, Taatjes DJ, Lee PJ, Mossman BT. (2008) Targeting the MEK1 cascade in lung epithelium inhibits proliferation and fibrogenesis by asbestos. Am. J. Respir. Cell Mol. Biol. 38, 618-626.
  • Zaman AKMT, Fugii S, Schneider DJ, Taatjes DJ, Lijnen HR, Sobel BE. (2007) Deleterious effects of lack of cardiac PAI-1 after coronary occlusion in mice and their pathophysiologic determinants. Histochem. Cell Biol. 128, 135-145.
  • Hatle KM, Neveu W, Dienz O, Rymarchyk S, Barrantes R, Hale S, Farley N, Lounsbury KM, Bond JP, Taatjes DJ, Rincon M. (2007) MCJ promotes c-Jun degradation to prevent ABCB1 transporter expression. Mol. Cell Biol. 27, 2952-2966.
  • Trott JF, Farley NR, Taatjes DJ, Hovey RC. (2007) Cloning and functional characterization of allelic variation in the porcine prolactin receptor. Domest. Anim. Endocrinol. 33, 313-334.
  • Taatjes DJ, Wadsworth MP, Zaman AK, Schneider DJ, Sobel BE. (2007) A novel dual staining method for identification of apoptotic cells reveals a modest apoptotic response in infarcted mouse myocardium.
     Histochem Cell Biol. 128, 275-83.
  • Storch KN, Taatjes DJ, Bouffard NA, Locknar S, Bishop NM, Langevin HM. (2007) Alpha-Smooth muscle actin distribution in cytoplasm and nuclear invaginations of connective tissue fibroblasts. Histochem. Cell Biol. 127, 523-530.
  • Shukla A, Lounsbury KM, Barrett TF, Gell J, Rincon M, Butnor KJ, Taatjes DJ, Davis GS, Vacek P, Nakayama KI, Steele C, Mossman BT. (2007) Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice. Am. J. Pathol. 170, 140-151.

Atomic Force Microscope

 

  • Headrick, R. L., et al. (2019). "Coherent X-ray measurement of step-flow propagation during growth on polycrystalline thin film surfaces." Nat Commun 10(1): 2638.
  • Braet, F., et al. (2018). "Probing the unseen structure and function of liver cells through atomic force microscopy." Semin Cell Dev Biol 73: 13-30. 
  • Headrick, R. J., et al. (2018). "Structure-Property Relations in Carbon Nanotube Fibers by Downscaling Solution Processing." Adv Mater 30(9).
  • Li, Y., et al. (2018). "Measuring adhesion between steel and early-hydrated Portland cement using particle probe scanning force microscopy." Cement and Concrete composites 90: 126-135.            
  • McKenzie, A. J., et al. (2018). "The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation." Sci Rep 8(1): 7228.
  • Rand, J. H. and D. J. Taatjes (2018). "Reimagining the antiphospholipid syndrome, an enigmatic thrombophilic disorder, through the looking glass of microscopic imaging." Histochem Cell Biol 150(5): 529-543.
  • Li, Y., et al. (2017). "Adhesion between modified binders and aggregate minerals at ambient conditions measured with particle-probe scanning force microscopes." Journal of Materials in Civil Engineering.              
  • Li, Y., et al. (2017). "Statistical analyses of aggregate mineral-binder adhesion: measuring with particle probe scanning force microscopes." Transportation Research Record 2632(1): 25-21.
  • Taatjes, D. J., et al. (2017). "Visualization of macro-immune complexes in the antiphospholipid syndrome by multi-modal microscopy imaging." Micron 100: 23-29.
  • Tan, T., et al. (2017). An experimental study of adhesion between aggregate minerals and asphalt binders using particle probe scanning force microscopy. International multiconference of engineers and computer scientists: 109-120.               
  • Tan, T., et al. (2017). Quantification of aggregate-binder adhesion in asphalt mixtures using particles probe scanning force microscopes. International MultiConference of Engineers and Computer Scientists, Hong Kong.
  • Li, Y., et al. (2016). "Nucleation and strain-stabilization during organic semiconductor thin film deposition." Sci Rep 6: 32620. 
  • Li, Y., et al. (2016). "Measuring adhesion between modified asphalt bindrs and aggregate minerals: use of particle probe scanning force microscopes." Transportation Research Record.
  • Previs, M. J., et al. (2016). "Phosphorylation and calcium antagonistically tune myosin-binding protein C's structure and function." Proc Natl Acad Sci U S A 113(12): 3239-3244.
  • Bezati, E., Wu, X-X., Quinn, A., Taatjes, D.J., and Rand, J.H. (2015) A new trick for an ancient drug: Quinine dissociates antiphospholipid immune complexes. Lupus 24, 32-41.
  • Quinn. A.S., Wu, X-X., Rand, J.H., and Taatjes, D.J. (2012) Insights into the pathophysiology of the antiphospholipid syndrome provided by atomic force microscopy. Micron 43, 851-862.
  • Rand, J.H., Wu, X-X., Quinn, A.S., and Taatjes, D.J. (2010) The annexin A5-mediated pathogenic mechanism in the antiphospholipid syndrome: role in pregnancy losses and thrombosis. Lupus 19, 460-469.
  • Rand JH, Wu X-X, Quinn AS, Ashton AW, Chen PP, Hathcock JJ, Andree AAM, Taatjes DJ. (2010) Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drug. Blood. 115, 2292-2299.
  • Rand JH, Wu X-X, Quinn AS, Chen PP, Hathcock JJ, Taatjes DJ. (2008) Hydroxychloroquine directly reduces the binding of anthiphospholipid antibody-Beta2-glycoprotein I complexes to phospholipid bilayers. Blood. 112, 1687-1695.

Light Microscopy

 

  • Anathy, V., et al. (2018). "Reducing protein oxidation reverses lung fibrosis." Nat Med 24(8): 1128-1135.
  • Ather, J. L., et al. (2018). "Serum Amyloid A3 is required for normal lung development and survival following influenza infection." Sci Rep 8(1): 16571.
  • Ko, N. L., et al. (2018). "Venoarterial communication mediates arterial wall shear stress-induced maternal uterine vascular remodeling during pregnancy." Am J Physiol Heart Circ Physiol 315(3): H709-H717.
  • Li, Z., et al. (2018). "Effect of TTC Treatment on Immunohistochemical Quantification of Collagen IV in Rat Brains after Stroke." Transl Stroke Res 9(5): 499-505.
  • Qian, X., et al. (2018). "IL-1/inhibitory kappaB kinase epsilon-induced glycolysis augment epithelial effector function and promote allergic airways disease." J Allergy Clin Immunol 142(2): 435-450 e410.
  • Marsden, C. G., et al. (2017). "Base Excision Repair Variants in Cancer." Methods Enzymol 591: 119-157.
  • Habibovic, A., et al. (2016). "DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma." JCI Insight 1(18): e88811.
  •  Hoffman, S. M., et al. (2016). "Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness." J Allergy Clin Immunol 137(3): 822-832 e827.
  •  Hoffman, S. M., et al. (2016). "Ablation of the Thiol Transferase Glutaredoxin-1 Augments Protein S-Glutathionylation and Modulates Type 2 Inflammatory Responses and IL-17 in a House Dust Mite Model of Allergic Airway Disease in Mice." Ann Am Thorac Soc 13 Suppl 1: S97.
  •  Hoffman, S. M., et al. (2016). "Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice." Am J Respir Cell Mol Biol 55(3): 377-386.
  •  Hristova, M., et al. (2016). "Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses." J Allergy Clin Immunol 137(5): 1545-1556 e1511.
  • McMillan, D. H., et al. (2016). "Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase pi." JCI Insight 1(8).
  • Platz, J., et al. (2016). "Comparative Decellularization and Recellularization of Wild-Type and Alpha 1,3 Galactosyltransferase Knockout Pig Lungs: A Model for Ex Vivo Xenogeneic Lung Bioengineering and Transplantation." Tissue Eng Part C Methods 22(8): 725-739.
  •  Pothen, J. J., et al. (2016). "A Computational Model of Cellular Engraftment on Lung Scaffolds." Biores Open Access 5(1): 308-319.
  • Siddesha, J. M., et al. (2016). "Effect of a chemical chaperone, tauroursodeoxycholic acid, on HDM-induced allergic airway disease." Am J Physiol Lung Cell Mol Physiol 310(11): L1243-1259.
  •  van der Velden, J. L., et al. (2016). "JNK inhibition reduces lung remodeling and pulmonary fibrotic systemic markers." Clin Transl Med 5(1): 36.
  • Fonseca, C., Taatjes, D.J., Callas, P., Ittleman, F., and Bovill, E.G. (2012) The effects of aging on the intimal region of the human saphenous vein: Insights from multimodal microscopy and quantitative image analysis. Histochem. Cell Biol. 138, 435-45.
  • Fukagawa NK, Li M, Sabo-Atwood T, Timblin CR, Butnor KJ, Gagne J, Steele C, Taatjes DJ, Huber S, Mossman BT. (2008) Inhaled asbestos exacerbates atherosclerosis in apolipoprotein E-deficient mice via CD4+ T cells. Environ. Health Perspec. 116, 1218-1225.
  • Manning CB, Sabo-Attwood T, Robledo RF, MacPherson MB, Rincon M, Vacek P, Hemenway D, Taatjes DJ, Lee PJ, Mossman BT. (2008) Targeting the MEK1 cascade in lung epithelium inhibits proliferation and fibrogenesis by asbestos. Am. J. Respir. Cell Mol. Biol. 38, 618-626.
  • Zaman AKMT, Fugii S, Schneider DJ, Taatjes DJ, Lijnen HR, Sobel BE. (2007) Deleterious effects of lack of cardiac PAI-1 after coronary occlusion in mice and their pathophysiologic determinants. Histochem. Cell Biol. 128, 135-145.
  • Shukla A, Lounsbury KM, Barrett TF, Gell J, Rincon M, Butnor KJ, Taatjes DJ, Davis GS, Vacek P, Nakayama KI, Steele C, Mossman BT. (2007) Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice. Am. J. Pathol. 170, 140-151.
  • Bostrom MA, Boyanovsky BB, Jordan CT, Wadsworth MP, Taatjes DJ, de Beer FC, Webb NR. (2007) GV sPLA2 promotes atherosclerosis: Evidence from genetically altered mice. Arterioscler. Thromb. Vasc. Biol. 27, 600-606.

Laser Capture Microdissection

 

  • Manning CB, Sabo-Attwood T, Robledo RF, MacPherson MB, Rincon M, Vacek P, Hemenway D, Taatjes DJ, Lee PJ, Mossman BT. (2008) Targeting the MEK1 cascade in lung epithelium inhibits proliferation and fibrogenesis by asbestos. Am. J. Respir. Cell Mol. Biol. 38, 618-626.

Super Resolution Microscopy

 

  • Lombardo, A. T., et al. (2019). "Myosin Va transport of liposomes in three-dimensional actin networks is modulated by actin filament density, position, and polarity." Proc Natl Acad Sci U S A 116(17): 8326-8335.
  • Clemments, A. M., et al. (2017). "Spatial Mapping of Protein Adsorption on Mesoporous Silica Nanoparticles by Stochastic Optical Reconstruction Microscopy." J Am Chem Soc 139(11): 3978-3981.
  • Lombardo, A. T., et al. (2017). "Myosin Va molecular motors manoeuvre liposome cargo through suspended actin filament intersections in vitro." Nat Commun 8: 15692.
  • Roy NH, Chan J, Lambelé M, Thali M. (2013) Clustering and Mobility of HIV-1 Env at Viral Assembly Sites Predict Its Propensity To Induce Cell-Cell Fusion. J Virol. Jul;87(13):7516-25.

Image Analysis Software

 

  • Taatjes D.J.; Ghule P.N., B. N. A., Lee K., DeLance N.M., Evans M.F., Weaver D.L., Deakin N., Carr F.E., Sprague B.L., Stein G.S., Stein J.L. (2022). "The Shared Core Resource as a Partner in Innovative Scientific Research: Illustration from an Academic Microscopy Imaging Center." Journal of Biomedical Techniques 33(1).
  • Gillis, N. E., et al. (2018). "Thyroid Hormone Receptor beta Suppression of RUNX2 Is Mediated by Brahma-Related Gene 1-Dependent Chromatin Remodeling." Endocrinology 159(6): 2484-2494.
    Tracy, K. M., et al. (2018). "Mitotically-Associated lncRNA (MANCR) Affects Genomic Stability and Cell Division in Aggressive Breast Cancer." Mol Cancer Res 16(4): 587-598.
  • van der Velden, J. L., et al. (2018). "TGF-beta1-induced deposition of provisional extracellular matrix by tracheal basal cells promotes epithelial-to-mesenchymal transition in a c-Jun NH2-terminal kinase-1-dependent manner." Am J Physiol Lung Cell Mol Physiol 314(6): L984-L997.
  • Mirando, A. C., et al. (2017). "Assessing the effects of threonyl-tRNA synthetase on angiogenesis-related responses." Methods 113: 132-138.
  • Thompson, J. K., et al. (2017). "Asbestos-Induced Mesothelial to Fibroblastic Transition Is Modulated by the Inflammasome." Am J Pathol 187(3): 665-678.
  • Habibovic, A., et al. (2016). "DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma." JCI Insight 1(18): e88811.
  • Smith, K. P., et al. (2016). "Inner-membrane protein MorC is involved in fimbriae production and biofilm formation in Aggregatibacter actinomycetemcomitans." Microbiology 162(3): 513-525.






IVIS Whole Animal Imager

 

  • Taipaleenmaki, H., et al. (2016). "Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells." Oncotarget 7(48): 79032-79046.

Whole Slide Scanner

 

  • Kumar, A., et al. (2022). "Inhibition of PDIA3 in club cells attenuates osteopontin production and lung fibrosis." Thorax 77(7): 669-678.
  • van de Wetering, C., et al. (2020). "Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease." J Immunol.
  • Nakada, E. M., et al. (2019). "Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresponsiveness by inhibiting UPR transducers." JCI Insight 4(9).
  • Taatjes, D. J., et al. (2019). "Quantitative pixel intensity- and color-based image analysis on minimally compressed files: implications for whole-slide imaging." Histochem Cell Biol 152(1): 13-23.
  • Tykocki, N. R., et al. (2018). "Development of stress-induced bladder insufficiency requires functional TRPV1 channels." Am J Physiol Renal Physiol 315(6): F1583-F1591.
  • Uhl, F. E., et al. (2017). "Preparation of Decellularized Lung Matrices for Cell Culture and Protein Analysis." Methods Mol Biol 1627: 253-283.
  • Cunniff, B., et al. (2015). "Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma." PLoS One 10(5): e0127310.