Hudziak Lab Research

Area of interest

  • ADHD, aggression, depression, developmental psychopathology and wellness.
  • Physician education through telemedicine online education systems.
  • Genetic and environmental influences on developmental psychopathology and wellness

Genomics of developmental trajectories in twins

A tremendous amount of research energy has been dedicated to demonstrating the importance of genetic influences on developmental psychopathologies in children. To date a convincing argument can be made that all of the developmental psychopathologies are influenced, at least in part, by genetic factors. Behavioral genetic approaches have yielded heritability estimates as high as 80% for some phenotypes (Attention Deficit Hyperactivity Disorder), with the majority of disorders influenced in roughly equal parts by genetic and environmental influences (e.g. Anxious/ Depression). The search for the specific genomic influences has included a wide variety of molecular approaches

Role: Primary Investigator

Determinants of Adolescent Exercise Behavios; towards Evidence-Based Intervention

This application proposes the first single nucleotide polymorphism (SNP)/copy number variation and (CNV) genome-wide association study of common childhood psychopathologies using an extended twin-sibling family study design. DNA has already been collected from a large sample of children and siblings who have been followed from birth until age 22 and their parents. This study will allow us to identify new genetic influences on child psychiatric illness which in turn will lead to improved diagnostic and treatment approaches.

Role: Primary Investigator

Patterns of Mood and Anxiety Disorders in Parents of Clinically Referred Children: Laying the Foundation for a Family-Based Approach to Mental Health in Singapore

The primary aim of this study is to characterize patterns of psychiatric diagnosis and mental health problems among the parents of clinically-referred youth with mood and anxiety disorders in Singapore.

PI: Dr. Sharon Cohan Sung
Role: Foreign Collaborator

Klingestion Third Generation Foundation. "Donald J. Cohen Medical Student Training Program"

The goals of the program, in keeping with the mission of the Department of Psychiatry and the Division of Child and Adolescent Psychiatry within the Vermont Center for Children, Youth, and Families:

  1. to create positive mentoring relationships between medical students and child psychiatrists
  2. to teach empirically-based and family-centered assessment
  3. to encourage students to consider a career in child and adolescent psychiatry

Role: Mentor