News and Events

LaMantia Takes on Lead Role for UVM Center on Aging

Michael LaMantia, M.D.Michael LaMantia, M.D., M.P.H., has been appointed director of the UVM Center on Aging, an interdisciplinary effort that serves the aging population in Vermont through research, education and public policy initiatives. LaMantia, who is associate professor in the Division of General Internal Medicine and Geriatrics, as well as section head of geriatric medicine, succeeds William Pendlebury, M.D., professor emeritus of pathology and laboratory medicine, who has served as the Center on Aging’s director for more than nine years. Established in 2008 with support from a generous endowment from Vermont philanthropist Lois McClure, the Center on Aging at UVM has a mission to forge an ongoing collaboration among faculty, students, staff and programs within the UVM, UVM Medical Center, and the Vermont community to promote a sense of wellbeing and a high quality of life for older adults. Read more.


Toth Leads a Cyber Approach to Knee Injury Rehab

Michael Toth, Ph.D.A collaboration between Michael Toth, Ph.D., professor in the Division of Cardiovascular Medicine, and faculty and students from UVM’s computer science program has resulted in a prototype mobile app that stands to help patients recover from traumatic knee injury. In early 2017, Toth and Christopher Skalka, Ph.D., were awarded one of two inaugural UVM Biomedical Engineering Pilot Research Program grants for their project, which is focused on creating a cyber-physical electrical stimulation system that acts as a bridge therapy for patients immediately post-injury and in the time between surgery and the start of physical therapy. Their idea is simple in concept– a Bluetooth-enabled personal neuromuscular electrical stimulation device that collects detailed data about device usage in real-time and sends these data to a mobile phone app. On the other end of the data stream, a backend server hosts an automated compliance analysis algorithm that analyzes the data and sends the care provider and the patient either “in” or “out of compliance” messages. If successful, the device will be the first of its kind to provide real-time monitoring of at-home rehabilitation using NMES. Read more.

 

Faculty Garner UVM Research and Mentor Awards

Beth Kirkpatrick, M.D.Several Department of Medicine faculty members were honored at the annual Dean’s Excellence in Research Awards event at the Larner College of Medicine held November 13, 2017. The awards ceremony recognized the accomplishments of faculty, residents, medical students, graduate students and postdoctoral trainees. Keynote speaker for the event was Jon Lorsch, Ph.D., director of the National Institute of General Medical Sciences. He hosted a talk, titled "Basic Research: The Foundation on Which Advances in Medicine are Built." Among the highlights shared during the State of Research at the College presentation were such achievements as 1,168 peer-reviewed publications in 2016, a new $20 million Northern New England Clinical and Translational Research Network grant with Maine Medical Center, and a commitment to the development of a new Health Services Research Center. Read more.

Awardees from the Department of Medicine included:

    UVM Health Network Medical Group Awards
  • Junior Researcher of the Year: Kim Dittus, M.D., Ph.D., assistant professor in the Division of Hematology/Oncology
  • Senior Researcher of the Year: Beth Kirkpatrick, M.D., professor in the Division of Infectious Disease (above)
    Larner College of Medicine Faculty Award
  • Mid-Career Investigator: Christopher Huston, M.D., associate professor in the Division of Infectious Disease
    Trainee Awards
  • Trainee Award for Outstanding Research Publication/Medical Student: Katharine Runte, M.D. (mentor: Markus Meyer, M.D., associate professor in the Division of Cardiovascular Disease)
  • Trainee Award for Outstanding Research Publication/Residents: Kara Landry, M.D., Clinical Instructor in Medicine (mentor: Mary Cushman, M.D., M.Sc., professor in the Division of Hematology/Oncology)

 

Awards and Recognition

Zail Berry, M.D.Zail Berry, M.D., M.P.H., associate professor in the Division of General Internal Medicine and Geriatrics, was the recipient of the inaugural Madison-Dean Award for Excellence in End-of-Life Care from The Madison-Dean Education Fund. The program was established by Joan Madison, M.D., and Estelle Deane, who both lost their physician husbands to pancreatic cancer. Their aim was to expand education for physicians and caregivers in advancing quality care for those who are dying and to encourage them to serve as catalysts for the acceptance of death as a natural part of life. The program’s mission is to transform end-of-life care through education, collaboration and inspiration. (Pictured from L to R: Zail Berry, M.D.; Joan Madison, M.D.; Estelle Dean) Read more.

Jennifer Gilwee, M.D., assistant professor and division chief for the Division of General Internal Medicine and Geriatrics, was named a fellow in the American College of Physicians in November of 2017. This is a distinction earned from colleagues who recognize a physician’s “accomplishments and achievements over and above the practice of medicine.” A graduate of the Larner College of Medicine, Gilwee completed her residency training at Rhode Island Hospital. Her research interests include the use of the medical home model in primary care practices.

New National Service and Leadership Roles
  • Gilman Allen, M.D., professor in the Division of Pulmonary Disease and Critical Care Medicine, has received a three-year appointment as a member of Annual Program Planning Committee for the Society of Critical Care Medicine.
  • Harold Dauerman , M.D., professor in the Division of Cardiovascular Medicine, has been named a member of the steering committee for New England Structural Heart Research and Education Consortium.
  • Anne Dixon, M.A., B.M., B.Ch., professor and division chief for the Division of Pulmonary Disease and Critical Care Medicine, has been elected to the American Board of Internal Medicine, Pulmonary Disease Board.
  • Prospero Gogo, M.D., associate professor in the Division of Cardiovascular Medicine, has been named a member of executive board for the American College of Cardiology Political Action Committee.
  • Glenn Goldman, M.D., professor and division chief for the Division of Dermatology, was appointed to serve on the board of directors for the American Society for Dermatologic Surgery.
  • Matthew Kinsey, M.D., assistant professor in the Division of Pulmonary Disease and Critical Care Medicine, was elected to the board of directors for the American Association of Bronchology and Interventional Pulmonology.
  • Michael LaMantia, M.D. M.P.H., associate professor in the Division of General Internal Medicine and Geriatrics, has joined the Leadership Board of the Vermont Chapter of the Alzheimer’s Association.
  • Bonita Libman, M.D., professor and division chief for the Division of Rheumatology and Clinical Immunology, was selected to be a member of the American College of Rheumatology Division Directors Special Committee in November of 2017.

 

Faculty and Staff News

faculty-engagement02Faculty in the Department of Medicine gathered at The Guild in Burlington on January 18 to connect with each other while enjoying some food and drink, courtesy of an event hosted by the Faculty Engagement Committee. The goal of the group is to facilitate communication and interaction between all faculty in the Department of Medicine, and make sure there's ample opportunity for faculty in different divisions to get to know each other and collaborate for research and mentorship. See a photo slideshow.



Meghan Foster, R.N., received her certificate in Ambulatory Nursing. She works in the Division of Rheumatology and Clinical Immunology.

Harold Dauerman, M.D., professor in the Division of Cardiovascular Medicine, has been named network director for Interventional Cardiology, UVM Health Network.

Lindsay Smith, M.D., assistant professor in the Division of Infectious Disease, is a key leader for a new antibiotic stewardship program in Vermont. Area hospitals are signing up to participate in the program, which collects data on the usage of antimicrobials to prevent healthcare associated infections and reduce antimicrobial resistance.

New Faculty

rodriguez familyThe family of Perdomo Rodriguez, M.D., traveled from Bogota, Colombia, to Burlington to celebrate the completion of his fellowship and his new position as an attending physician and assistant professor in the Division of Endocrinology, Diabetes and Metabolism. From left to right: sister Carolina Perdomo; father Nestor Perdomo, M.D.; sister Laura Perdomo, MS II; mother Maria Rodriguez, R.N.; Perdomo Rodriguez, M.D.; and wife Jessica Guzman, R.N.




Alana Nevares, M.D., joined the Division of Rheumatology and Clinical Immunology as an assistant professor in October of 2017. Her areas of special interest include vasculitis, anti-synthetase syndrome, non-infectious uveitis, and systemic autoimmune conditions. Dr. Nevares also treats common rheumatologic disorders such as gout and rheumatoid arthritis. She completed a fellowship in rheumatology at the Cleveland Clinic Foundation, and residency training at John H. Stroger Hospital of Cook County. She is a graduate of University Nacional Autonoma De Nicaragua Fac De Ciencia.

Electronic Health Record Update

Stay tuned for a feature story in the spring issue of The Chart regarding electronic health record system upgrades across the UVM Health Network. View the implementation timeline.

 

Education News

Laurie Leclair, M.D.Students in the Larner College of Medicine Class of 2020 recognized the outstanding teaching and leadership of Laurie Leclair, M.D., professor in the Division of Pulmonary Disease and Critical Care Medicine, at the Foundations Awards Celebration in January of 2018. The event celebrates the end of the Foundations level of the Vermont Integrated Curriculum for the first-year students, and honors faculty and staff who helped them along the way. Leclair received the Outstanding Foundations Course Award for Cardiovascular, Respiratory and Renal Systems, which she directs, and she received the Dean Warshaw Integration Award, which honors a faculty member whose teaching best captured the spirit of the Vermont Integrated Curriculum.

Kim Dittus, M.D., Ph.D., and Patricia O’Brien, M.D., both assistant professors in the Division of Hematology/Oncology, served as mentors to two Larner College of Medicine students who received a 2017-18 Schweitzer Fellowship to create Step Up, a weight loss group for women cancer survivors. The 12-week behaviorally-based intervention enrolled 17 female cancer survivors with a body mass index of greater than 30. The program featured weekly, hour-long classes at the UVM Medical Center’s rehabilitation gym, and mentoring from Donnelly and Martin. Using journaling, calorie and exercise goals, and individualized feedback, the program helped participants make lifestyle changes that they will carry with them well after completing the program. Step Up was featured in the Burlington Free Press and on the Schweitzer Fellows blog. Read more.

Marvin Klikunas, M.D., associate professor in the Division of General Internal Medicine and Geriatrics and the 2017 UVM faculty recipient of the Leonard Tow Humanism in Medicine Award, delivered the keynote presentation at 2017 White Coat Ceremony for the Larner College of Medicine Class of 2021. During this ceremony, 119 first-year medical students received their first white doctors’ coats, symbols of their commitment to be respectful and compassionate towards not only patients, but all members of the healthcare team, and to cultivate attitudes and behaviors that are sensitive to others’ values and their cultural and ethnic backgrounds. Read Klikunas’ remarks on the Larner College of Medicine blog.

Neil Zakai, M.D., M.Sc., associate professor in the Division of Hematology/Oncology, was faculty for the American Society of Hematology’s Clinical Research Training Institute in August of 2017.

Recent Distinguished Guest Speakers

David Goff, M.D., Ph.D.The Department of Medicine hosted David C. Goff, M.D., Ph.D., as the Cardiovascular Research Institute of Vermont Burton Sobel Visiting Professor in October of 2017. Goff is the director of the Division of Cardiovascular Sciences at the National Heart, Lung, and Blood Institute. His programs included an interactive discussion titled “Where's the Funding Going: NHLBI Strategic Vision Implementation for the Division of Cardiovascular Sciences,” and a Medicine Grand Rounds titled “Eliminating Cardiovascular Disparities Through Community-Engaged Research: A thought exercise.” Dr. Goff also met with several small thematic research groups from a variety of Larner College of Medicine departments, and met extensively with early career investigators. The visit was coordinated by coordinated by Mary Cushman, M.D., M.Sc., professor in the Division of Hematology/Oncology.

In September of 2017, the Department of Medicine welcomed Joseph Ouslander, M.D., as the invited Tisdale Speaker. Dr. Ouslander is professor and senior associate dean for geriatric programs and chair of the Department of Integrated Medical Science at the Charles E. Schmidt College of Medicine of Florida Atlantic University in Boca Raton, Florida. An internationally recognized geriatrician, he is a past-president of the American Geriatrics Society, and serves as the executive editor of the society’s Journal. He is a co-author of Essentials of Clinical Geriatrics and an editor of Principles of Geriatric Medicine and Gerontology.

 

Research and Grants

Gilman Allen, M.D., professor in the Division of Pulmonary Disease and Critical Care Medicine, recently wrapped up data collection on patient- and family-centered rounding in the MICU and SICU for a collaborative, multi-centered project from the Society of Critical Care Medicine and Patient Centered Outcomes Research Institute.

Two new articles from Mary Cushman, M.D., M.Sc., Neil Zakai, M.D., M.Sc., and colleagues open up a new line of research on the importance of galectin-3 in vascular-related diseases. The team is now evaluating whether galectin-3, an inflammatory marker that also has procoagulant activity, relates to risk of cognitive impairment. In the Atherosclerosis Risk in Communities (ARIC) Study, higher levels of galectin-3 were associated with increased risk of future venous thrombosis. In the REGARDS cohort, in work started by Zubin Agarwal, M.D., when he was an internal medicine resident at UVM Medical Center, we reported that higher levels of galectin-3 were associated with stroke risk over five years, but only in younger people (<64 at baseline). The risk is very high, at a doubling for those with levels in the top quartile.

  • Fashanu OE, Heckbert SR, Aguilar D, Jensen PN, Ballantyne CM, Basu S, Hoogeveen RC, deFilippi C, Cushman M, Folsom AR. Galectin-3 and venous thromboembolism incidence: the Atherosclerosis Risk in Communities (ARIC) Study. Res Pract Thromb Haemost 2017;1:223-30.
  • Arora P, Agarwal Z, Venkatraman A, Callas PW, Kissela B, Jenny N, Judd SE, Zakai NA, Cushman M. Galectin-3 and risk of ischemic stroke in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort. Eur J Neurol 2017;24:1464-70.


Anne Dixon, M.A., B.M., B.Ch., professor and division chief for the Division of Pulmonary Disease and Critical Care Medicine, launched the Pilot of Lifestyle in Asthma INtervention (PLAN). This collaboration with Jean Harvey, Ph.D., R.D., professor and chair of UVM’s Department of Nutrition and Food Sciences, is a pilot study to determine if an internet-based weight loss intervention will help patients suffering with obesity and poorly controlled asthma. This National Institutes of Health and American Lung Association-sponsored study will recruit patients at UVM and the University of Arizona.

The Area Health Education Centers (AHEC) program received grant renewal for five years beginning in September of 2017. In 1996, the Office of Primary Care was first awarded federal funding to establish a statewide AHEC program, which works to increase the supply, geographic distribution, and education of Vermont's healthcare workforce. Charles MacLean, M.D., professor in the Division of General Internal Medicine and Geriatrics, is the Larner College of Medicine Associate Dean for Primary Care.

Halle Sobel, M.D., associate professor in the Division of General Internal Medicine and Geriatrics, and colleagues demonstrated that a scheduling model matching faculty to internal medicine residents’ ambulatory block schedules increased resident and preceptor perceptions of familiarity with complex patients. The matched scheduling model also increased preceptor perceptions of comfort in assessing residents on milestones, although this effect was limited to assessments early in the academic year. Their findings were published in the August issue of the Journal of Graduate Medical Education. View the abstract. 

Daniel Weiss, M.D., Ph.D., professor in the Division of Pulmonary Disease and Critical Care Medicine, is co-investigator, along with Human Biomed Inc., for a $1,000,000 Medical Technology Enterprise Consortium project, titled "Development of Multi-Functional Extracorporeal Life Support (ECLS) System for Lung and Kidney Support Pneuma-K ECLS System." The goal is to develop and test a new combined dialysis-ECMO device.

 

House Staff News

Cardiology fellow Abraham Abernathy, M.D., recently had a paper accepted for publication in Journal of the American Heart Association with several UVM colleagues including Peter VanBuren, M.D., associate professor in the Division of Cardiovascular Medicine, Martin LeWinter, M.D., professor in the Division of Cardiovascular Medicine, and former cardiology fellow Sadi Raza, M.D. The study, titled “Pro-inflammatory Biomarkers in Stable Versus Acutely Decompensated Heart Failure With Preserved Ejection Fraction," was performed in collaboration with the Duke Cardiovascular Research Institute and the NHLBI Heart Failure Research Network.

Second-year hematology/oncology fellow Dan Douce, M.D., was featured on Thrombosis TV, where he discussed the risk stratification for VTE in cancer outpatients using an enhanced Khorana score. Watch the segment. 

Second-year endocrinology, diabetes and metabolism fellow Amanda Fernandes, M.D., has accepted the New England Journal of Medicine Editorial Fellowship for next year.

Prateek Ghatage, M.B.B.S., will be joining the Division of Infectious Disease as a fellow in July of 2018. He is currently an internal medicine resident at Monmouth Medical Center in New Jersey, and is a graduate of Seth G.S. Medical College.

The most recent graduated fellow from the Division of Infectious Disease, Porntip Kiatsimkul, M.D., passed the board certification exam, maintaining our 100 percent board pass rate for the fellowship program.

The Division of Dermatology is training an Israeli fellow, Yoav Metzger, M.D., in dermatologic surgery/Mohs surgery. Metzger will return to Israel to practice Mohs surgery.

 

In the Media

Mary Cushman, M.D., M.Sc., professor in the Division of Hematology/Oncology, was widely quoted in the media regarding an abstract presented at the American Heart Association Fall Sessions that reported that people who watch television most frequently have a 70 percent increased risk of venous thromboembolism. The association persisted even among those who had the recommended amount of exercise or without obesity. Read the story in Time magazine.

Garth Garrison, M.D., assistant professor in the Division of Pulmonary Disease and Critical Care Medicine, was interviewed for a WCAX-TV segment that aired on November 22, 2017, titled “Vermont Doctors Want You to Get a Lung Cancer Screening.” Watch the segment.

Prospero Gogo, M.D., associate professor in the Division of Cardiovascular Medicine, was interviewed on Fox 22 regarding his proposal to the Burlington City Council to add to the Town Meeting Day ballot an item that asks ask voters if they would like to recommend to the state legislature raising the minimum age to buy tobacco to 21. The council approved the measure. Watch the segment that aired December 18, 2017.

Mia Hockett, M.D., assistant professor in the Division of General Internal Medicine and Geriatrics, was a guest on a PBS NewsHour segment, titled “Vermont’s rules on vaccines for school met with parent’s support and pushback.” Watch the segment that aired September 26, 2017.

Michael LaMantia, M.D., M.P.H., associate professor in the Division of General Internal Medicine/Geriatrics, was a guest on Vermont Public Radio’s Vermont Edition, where he discussed “Aging Well” with host Bob Kinzel and Vermont Commissioner of Disability, Aging, and Independent Living Monica Hutt. Listen to the segment that aired November 17, 2017.

Keith Morley, M.D., assistant professor in the Division of Dermatology, is quoted in an article in Tonic, a website and digital video channel affiliated with Vice, titled “Growing a Beard Solved My Lifelong Acne Program. Read the story published December 12, 2017.

 

Who Knew?

treecollage

Mary Cushman, M.D., M.Sc., professor in the Division of Hematology/Oncology and William Pendlebury, M.D., professor emeritus of pathology and laboratory medicine, celebrated the holidays in style this year, with 10 Christmas trees decorated at their home.

weissDaniel Weiss, M.D., Ph.D., professor in the Division of Pulmonary Disease and Critical Care Medicine, organized another successful Green Mountain Mahler Festival performance of Beethoven's Symphony No. 9 on New Year's Day, raising funds for the Vermont Refugee Resettlement Program. Weiss' home division had a strong showing in the all-volunteer group this year, with two retired members playing key roles. Ted Marcy, M.D., was a chorus member, and Gerald Davis, M.D., was one of the percussionists. He played the bass drum.

Publications and Presentations

Publications

Division of Cardiovascular Medicine

Xing L, Higuma T, Wang Z, Aguirre AD, Mizuno K, Takano M, Dauerman HL et al. Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study. J Am Coll Cardiol 2017; 69: 2502-2513.

Dauerman HL and Rambod M. Registries, Reality and Complete Revascularization. Eurointervention 2017; 13: 383-385.

Dauerman HL. Bivalirudin Across the Atlantic. J Am Coll Cardiology: Cardiovascular Interventions 2017; 10:1112-1114.

Chava S, Gentchos G, Abernethy A, Leavitt B, Terrien E, Dauerman HL. Routine CT angiography to detect severe coronary artery disease prior to transcatheter aortic valve replacement. J Thromb Thrombolysis 2017; 44: 154-160.

Steiner J, Lewinter ML, Rhodes-Cabau J, Holmes D, Dauerman HL. Mechanical Interventions for Patients with Aortic Stenosis and Heart Failure with Reduced Ejection Fraction. J Am Coll Cardiol December 2017.

Azarbal A, Leadholm K, Ashikaga T, Solomon R, Dauerman HL. Acute Kidney Recovery after Transcatheter Aortic Valve Replacement. American Journal of Cardiology, March, 2018, in press.

Division of Dermatology

Thomas C, Morley K, Schmidt B, Hussain S. Subcutaneous granuloma annulare involving the scalp. Pediatr Dermatol. 2017; epub ahead of print.

Morley K, Treat J. Patient Perspectives: What is perioral dermatitis? Pediatr Dermatol. 2017;34(5):601-602.

Peterman CM, Morley KW, Tan JK, Liang, MG. Self-Limited Neonatal Periumbilical Erythema. Pediatr Dermatol. 2017; 34(6):730-731.

Morley KW, Butler LK, MacCormack MA, Tiger JB. Surgical Pearl: The Pinch Stitch. J Am Acad Dermatol. 2017; 77(3):e75-e76.

Loyal J, Sinclair NR, Hugh JM, Cook DL, Pierson JC. Sunburn purpura. Cutis. 2017 Oct;100(4):E15-E17

Division of Endocrinology, Diabetes and Metabolism

Bolton KC, Gilbert MP. A Case of Piezogenic Pedal Papules in a Man with Acromegaly. Endocr Pract. 2017 Nov 16. doi: 10.4158/EP-2017-0014. PMID: 29144816

Singh AK, Bodolan AA, Gilbert MP. A False Positive I-131 Metastatic Survey Caused by Radioactive Iodine Uptake by a Benign Thymic Cyst. Case Reports in Endocrinology. 2017 Dec; article ID 6469015. doi: 10.1155/2017/6469015.

Lee SL, Gilbert MP. Thymic cyst causes false-positive radioactive iodine scan. Endocrine Today 2017;15:13.

Division of Gastroenterology and Hepatology

Wieland R, Zubarik R, Zenali M. Distinct Presentation of a Neglected Tropical Disease on Screening Colonoscopy. Clinical Gastroentology and Hepatology, January 2017, Volume 15, Issue 1

Division of Hematology/Oncology

Engbers M, Blom JW, Cushman M, Rosendaal FR, van Hylckama Vlieg A. Functional impairment and risk of venous thrombosis in older people. J Am Geriatr Soc 2017;65:2003-8.

Gupta DK, Daniels LB, Cheg S, deFilippi CR, Criqui MH, Maisel MS, Lima JA, Bahrami H, Greenland P, Cushman M, Tracy R, Siscovick D, Bertoni AG, Cannone V, Burnett JC, Carr JJ, Wang TJ. Differences in natriuretic peptide levels by race/ethnicity (from the Multi-Ethnic Study of Atherosclerosis. Am J Cardiol 2017;120:1008-15.

Wong ND, Zhao Y, Quek RGW, Blumenthal RS, Budoff MJ, Cushman M, Garg P, Sandfort V, Tsai M, Lopez JAG. Residual atherosclerotic cardiovascular disease risk in statin-treated adults: the Multi-Ethnic Study of Atherosclerosis. J Clin Lipidol 2017;11:1223-33.

Kent ST, Rosenson RS, Avery CL, Chen YI, Correa A, Cummings SR, Cupples LA, Cushman M, Evans DS, Gudnason V, Harris TB, Howard G, Irvin MR, Judd SE, Jukema JW et al. PCSK9 loss-of-function variants, low density lipoprotein cholesterol, and risk of coronary heart disease and stroke: data from 9 studies of blacks and whites. Circ Cardiovasc Genet 2017;10:e001632.

Cushman M, Brink E. Indexing for a new journal: Research and Practice in Thrombosis and Haemostasis. Res Pract Thromb Haemost 2017;1:148-9.

Howard G, Kleindorfer D, Cushman M, Long DL, Jasne A, Judd SE, Higginbotham JC, Howard VJ. Contributors to the excess stroke mortality in rural areas in the United States. Stroke 2017;48:1773-8. (PMCID: PMC5502731)

Winovich DT, Longstreth WT Jr, Arnold AM, Varadhan R, Zeki Al, Hazzouri A, Cushman M, Newman AB, Odden MC. Factors associated with ischemic stroke survival and recovery in older adults. Stroke 2017;48:1818-26. (PubMed – in process)

Roetker NS, Armasu SM, Pankow JS, Lutsey PL, Tang W, Rosenberg MA, Palmer TM, MacLehose RF, Heckbert SR, Cushman M, de Andrade M, Folsom AR. Taller height as a risk factor for venous thromboembolism: a Mendelian randomization meta-analysis. J Thromb Haemost 2017;15:1334-43. (PMCID: PMC5504700)

Appiah D, Fashanu OE, Heckbert SR, Cushman M, Psaty BM, Folsom AR. Relation of coagulation factor XI with incident coronary heart disease and stroke: the Cardiovascular Health Study. Blood Coag Fibrinolysis. 2017; 28(5): 389-392. (PubMed – in process)

Vella CA, Allison MA, Cushman M, Jenny NS, Miles MP, Larsen B, Lakoski SG, Michos ED, Blaha MJ. Physical activity and adiposity-related inflammation: the MESA. Med Sci Sports Exerc., 2017; 49(5); 915-921. (PMCID: PMC5392139)

Harrington LB, Blondon M, Cushman M, Kaunitz AM, Rossouw JE, Allison MA, Martin LW, Johnosn KC, Rosing J, Woods NF, LaCroix AZ, Heckbert SR, McKnight B, Smith NL. The cross-sectional association between vasomotor symptoms and hemostatic parameter levels in postmenopausal women. Menopause. 2017; 24(4): 360-370. (PMCID: PMC5365368)

Harvey J, Dittus K, Mench E. eHealth and behavioral weight loss interventions for female cancer survivors: A review. Women’s Health (Lond). 2017 Sep 1:1745505717731012. doi: 10.000/jgs.14964. PMID: 28598535

Trentham-Dietz A, Ergun MA, Alagoz O, Stout NK, Gangnon RE, Hampton JM, Dittus K, James TA, Vacek PM, Herschorn SD, Burnside ES, Tosteson ANA, Weaver DL, Sprague BL. Comparative effectiveness of incorporating a hypothetical DCIS prognostic marker into breast cancer screening. Breast Cancer Res Treat. 2017 Nov 28. doi: 10.1007/s10549-017-4582-0. PMID: 29185118

Dittus KL, Gramling RE, Ades PA. Exercise interventions for individuals with advanced cancer: A systematic review. Prev Med. 2017 Jul 15. pii: S0091-7435(17)30262-1. doi: 10.1016/j.ypmed.2017.07.015. PMID: 2871665

Douce D, McClure LA, Lutsey P, Cushman M, Zakai NA. Outpatient treatment of deep vein thrombosis in the Unites States: the Reasons for Geographic and Racial Differences in Stroke Study. J Hosp Med 2017;12:826-30.

Zakai NA, Olson NC, Judd SE, Kleindorfer DO, Kissela BM, Howard G, Cushman M. Hemostasis biomarkers and risk of intracerebral hemorrhage in the Reasons for Georgraphic and Racial Differences in Stroke study. Thromb Haemost 2017;117:1808-15.

Raffield LM, Zakai NA, Duan Q, Laurie C, Smith JD, Irvin MR, Doyle MF, Naik RP, Song C, Manichaikul AW, Liu Y, Durda P, Rotter JI, Jenny NS, Rish SR, Wilson JG, Johnson AD, Correa A, Li Y, Nicherson DA, Rice K, Lange EM, Cushman M, Lange LA, Reiner AP for the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Hematology & Hemostasis TOPMed Working Group. D-dimer in African Americans: whole genome sequence analysis and relationship to CVD risk in the Jackson Heart Study. Arterioscler Thromb Vasc Biol 2017;37:2220-7.

Division of Infectious Disease

Jain V, Yogavel M, Kikuchi H, Oshima Y, Hariguchi N, Matsumoto M, Goel P, Touquet B, Jumani RS, Tacchini-Cottier F, Harlos K, Huston CD, Hakimi MA, Sharma A. Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis. Structure. 2017 Oct 3;25(10):1495-1505.e6. doi: 10.1016/j.str.2017.07.015. Epub 2017 Aug 31. PMID:28867614

Susheela AT, Hale A. Patients with common variable immunodeficiency paradoxically have increased rates of autoimmune disorders. BMJ Case Reports 2017; doi:10.1136/bcr-2017-221657 Unusual association of diseases/symptoms

Division of Pulmonary Disease and Critical Care Medicine

Keveson B, Clouser R, Hamlin M, Stevens P, Allen GB. Adding value to daily chest X-rays through education, restricted daily orders, and indication-based prompting. BMJ Open Quality 2017; 6:e000072. doi:10.1136/bmjoq-2017-000072

Bates JHT. CORP: Measurement of Lung Function in Small Animals. Journal of Applied Physiology. 123: 1039–1046, 2017.

Copot D, Ionescu CM, Lopes A, Machado JAT, Bates JHT. The Role of Fractional Calculus in Modelling Biological Phenomena: A review. Communications in Nonlinear Science and Numerical Simulation. 51: 141-159, 2017.

Bates JHT, Poynter ME, Frodella CM, Peters U, Dixon AE, Suratt BT. Pathophysiology to Phenotype in the Asthma of Obesity. Ann Am Thorac Soc 2017; 14: S395-S398.

Smith BJ, Bartolak-Suki B, Suki GS, Roy KL, Hamlington C, Charlebois C, Bates JHT. Linking ventilator injury-induced leak across the blood-gas barrier to derangements in lung function.” Frontiers in Physiology. July 2017. Doi: 10.3389/fphys.2017.00466

Dixon AE, Suratt BT. Chair's Summary: Obesity and Associated Changes in Metabolism, Implications for Lung Diseases. Ann Am Thorac Soc 2017; 14: S314-S315.

Nyenhuis SM, Dixon AE, Ma J. Impact of Lifestyle Interventions Targeting Healthy Diet, Physical Activity, and Weight Loss on Asthma in Adults: What Is the evidence? J Allergy Clin Immunol Pract 2017.

Qian X, Aboushousha R, van de Wetering C, Chia SB, Amiel E, Schneider RW, van der Velden JLJ, Lahue KG, Hoagland DA, Casey DT, Daphtary N, Ather JL, Randall MJ, Aliyeva M, Black KE, Chapman DG, Lundblad LKA, McMillan DH, Dixon AE, Anathy V, Irvin CG, Poynter ME, Wouters EFM, Vacek PM, Henket M, Schleich F, Louis R, van der Vliet A, Janssen-Heininger YMW. IL-1/inhibitory kappaB kinase epsilon-induced glycolysis augment epithelial effector function and promote allergic airways disease. J Allergy Clin Immunol 2017.

Hoyt LR, Randall MJ, Ather JL, DePuccio DP, Landry CC, Qian X, Janssen-Heininger YM, van der Vliet A, Dixon AE, Amiel E, Poynter ME. Mitochondrial ROS induced by chronic ethanol exposure promote hyper-activation of the NLRP3 inflammasome. Redox Biol. 2017 Aug;12:883-896.

Dixon AE, Castro M, Gerald LB, Holbrook JT, Henderson RJ, Casale TB, Irvin CG, Black K, Wise RA, Sugar EA. American Lung Association Airways Clinical Research Centers' Writing Committee Effect of intranasal corticosteroids on allergic airway disease in asthma. J Allergy Clin Immunol Pract. 2017 Jul - Aug;5(4):1125-1128.e3.

Hageman, HL, Huggett, KN, Simpson, D. et al. Operationalizing Interprofessional Education in the Clinical Workplace. Med.Sci.Educ. (2017).

Kaminsky DA, Hanania NA, Guntupalli KK, Lippman, J, Burns S, Brock M, Skelly J, DeSarno M, Pecott-Grimm H, Mohsin A, LaRock-McMahan C, Warren P, Whitney M. Effect of yoga breathing (pranayama) on exercise tolerance in patients with COPD: A randomized clinical trial. J Altern Complement Med 2017 Jul 17. PMID: 28714735

Kanagalingam S, Shehab SS, Kaminsky DA, Wise RA, Lang JE, Dixon AE. Effect of obesity on sinonasal disease in asthma. J Asthma. 2017 Jul 24:1-7.

Lugogo N, Francisco D, Addison KJ, Manne A, Pederson W, Ingram JL, Green CL, Suratt BT, Lee JJ, Sunday ME, Kraft M, Ledford JG. Obese asthmatic patients have decreased surfactant protein A levels: Mechanisms and implications. J Allergy Clin Immunol. 2017 Jun 15. pii: S0091-6749(17)30935-1. doi: 10.1016/j.jaci.2017.05.028. [Epub ahead of print] PMID: 28624607

Peters U, Suratt BT, Bates JHT, Dixon AE. Beyond BMI: Obesity and Lung Disease. Chest. 2017 Jul 17. pii: S0012-3692(17)31260-6. [Epub ahead of print] Review.

Suratt BT, Ubags NDJ, Rastogi D, Tantisira KG, Marsland BJ, Petrache I, Allen JB, Bates JHT, Holguin F, McCormack MC, Michelakis ED, Black SM, Jain M, Mora AL, Natarajan V, Miller YI, Fessler MB, Birukov KG, Summer RS, Shore SA, Dixon AE. An Official American Thoracic Society Workshop Report: Obesity and Metabolism. An Emerging Frontier in Lung Health and Disease. Ann Am Thorac Soc. 2017 Jun;14(6):1050-1059. doi: 10.1513/AnnalsATS.201703-263WS.

Armitage J, Tan D, Troedson R, Young P, Lam KV, Shaw K, Sturm M, Weiss DJ, Moodley Y. Mesenchymal stromal cell infusion modulates systemic immunological responses in stable COPD patients: A phase I pilot study. European Resp J, in press 2018

Weiss DJ, Turner L, Levine AD, Ikonomou L. Medical societies, patient education initiatives, public debate and marketing of unproven stem cell interventions. Cytotherapy. 2017 Nov 24. pii: S1465-3249(17)30714-4. doi: 10.1016/j.jcyt.2017.10.002. [Epub ahead of print] Uhl FE, Wagner DE, Weiss DJ. Preparation of Decellularized Lung Matrices for Cell Culture and Protein Analysis. Methods Mol Biol. 2017;1627:253-283. doi: 10.1007/978-1-4939-7113-8_18.

de Castro LL, Xisto DG, Kitoko JZ, Cruz FF, Olsen PC, Redondo PAG, Ferreira TPT, Weiss DJ, Martins MA, Morales MM, Rocco PRM. Human adipose tissue mesenchymal stromal cells and their extracellular vesicles act differentially on lung mechanics and inflammation in experimental allergic asthma. Stem Cell Res Ther. 2017 Jun 24;8(1):151. doi: 10.1186/s13287-017-0600-8.

Abreu SC, Antunes MA, Xisto DG, Cruz FF, Branco VC, Bandeira E, Zola Kitoko J, de Araújo AF, Dellatorre-Texeira L, Olsen PC, Weiss DJ, Diaz BL, Morales MM, Rocco PRM. Bone Marrow, Adipose, and Lung Tissue-Derived Murine Mesenchymal Stromal Cells Release Different Mediators and Differentially Affect Airway and Lung Parenchyma in Experimental Asthma. Stem Cells Transl Med. 2017 Jun;6(6):1557-1567. doi: 10.1002/sctm.16-0398.

Silva LH, Cruz FF, Morales MM, Weiss DJ, Rocco PR. Magnetic targeting as a strategy to enhance therapeutic effects of mesenchymal stromal cells. Stem Cell Res Ther. 2017 Mar 9;8(1):58. doi: 10.1186/s13287-017-0523-4.

de Oliveira HG, Cruz FF, Antunes MA, de Macedo Neto AV, Oliveira GA, Svartman FM, Borgonovo T, Rebelatto CL, Weiss DJ, Brofman PR, Morales MM, Lapa E Silva JR, Rocco PR. Combined Bone Marrow-Derived Mesenchymal Stromal Cell Therapy and One-Way Endobronchial Valve Placement in Patients with Pulmonary Emphysema: A Phase I Clinical Trial. Stem Cells Transl Med. 2017 Mar;6(3):962-969. doi: 10.1002/sctm.16-0315.

Jordan M, O’Keefe M, Weiss D, Cubberley CW, MacLean C, Wolfson D. Implementation of the Universal BLS Termination of Resuscitation Rule in a Rural EMS System. Resuscitation, 2017. DOI: 10.1016/j.resuscitation.2017.07.004

Presentations
Division of Dermatology

Keith Morley, M.D., was an invited speaker at several events, including:

  • Lumps and Bumps Forum. American Academy of Dermatology 75th Annual Meeting. Orlando, Fla., 2017.
  • Keynote Speaker at the Latest on Juvenile Dermatomyositis and Outreach Opportunities. Cure JM Massachusetts Chapter Meet & Greet. Framingham, Mass., 2017
Division of Endocrinology, Diabetes and Metabolism

Matthew Gilbert, M.D., recently presented several abstracts:

  • Perdomo-Rodriguez JP, Anderson S, Howard A, Gilbert MP. Implementation of a Multidisciplinary Thyroid Biopsy Clinic (MTBC) Reduces the Rate of Non-Diagnostic Cytology and the Number of Surgical Referrals. Poster ID # 2784074. American Thyroid Association Annual Meeting, October 18-22, 2017, Victoria, BC, Canada.
  • Fernandes A, Gilbert MP. A Mystic Cystic Mass: A Case of Benign Thymic Cyst in a Patient with Papillary Thyroid Cancer. New England-AACE, 9th Annual Meeting, October 14, 2017, Newton, MA, USA.
Division of Immunobiology

Ralph Budd, M.D., hosted a lecture at the National American College of Rheumatology Meeting, Basic Immunology Session showing that “MAVS is oligomerized in Lupus Patients’ Lymphocytes as a Mechanism for Production of Type I Interferon.”

Division of Pulmonary Disease and Critical Care Medicine

Kathryn Huggett, Ph.D., and William Jeffries, Ph.D., presented “Institutional Transformation to Evidence-Based Pedagogy: A Case Study Applying the Four-Frame Approach” at the Association of Medical Educators in Europe (AMEE) Conference in Helsinki, Finland, on August 28, 2017.

David Kaminsky, M.D., was guest speaker for Breathe New Hampshire Educational Conference in Manchester, NH, in November of 2017. His talk was titled “What is COPD Anyway? Enhancing COPD Management in Primary Care.”

Matthew Kinsey, M.D., attended the Asian Pacific Society of Respirology in Sydney, Australia, as an American Thoracic Society Young Investigator.

Benjamin Suratt, M.D., was invited to be part of an expert panel on pneumonia at NHLBI in August and to give a presentation there on the effects of metabolic changes on pneumonia pathogenesis and outcomes.

Division of Rheumatology and Clinical Immunology

Melinda Edwards R.N., Siobhan Farley, R.N., Carl Possidente, Pharm.D., FASHP, and Bonita Libman, M.D., presented a poster at the National American College of Rheumatology Meeting on November 5, 2017, titled “Nurse Telephone Education for Promoting a Treat-to-Target Approach in Recently Diagnosed Rheumatoid Arthritis Patients—A Preliminary Review.”

Siobhan Farley, R.N., presented a poster at the annual American College of Rheumatology Meeting for a project for newly-diagnosed Rheumatoid Arthritis patients.

Chi Chi Lau, M.D., delivered an oral abstract presentation on November 7, 2017 at the American College of Rheumatology Meeting in San Diego, Calif., on the study “Are We Over-Testing for Liver Enzyme Abnormalities in Rheumatoid Arthritis Patients Prescribed Methotrexate.”