Graduate and Postdoctoral Training

Like many inventions, the LOST-Wheel was born out of necessity and, jokes Bivona, out of spite. In his final years as a Cellular, Molecular, and Biomedical Sciences graduate student, Bivona worked on a grant-funded project in the laboratory of UVM Larner College of Medicine Professor of Medicine Matthew Poynter, Ph.D. The project, says Poynter, aims to determine the contribution of skeletal muscle contractile muscle cells (myocytes) to local and systemic inflammation and the potential benefits of exercise to diminish overexuberant or protracted inflammation. The work relies heavily on the study of mouse models after they exercise either on rodent treadmills (yes, they make treadmills for rodents) or on small circular machines commonly called mouse wheels.